CD55 molecule (Cromer blood group) (Q5248822)

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mammalian protein found in Homo sapiens

• CR
• CROM
• complement decay-accelerating factor
• CD55 molecule, decay accelerating factor for complement (Cromer blood group)
• CD55 antigen
• DAF
• CD55
• TC
• Cromer blood group antigen

edit

Language	Label	Description	Also known as
English	CD55 molecule (Cromer blood group)	mammalian protein found in Homo sapiens	CR CROM complement decay-accelerating factor CD55 molecule, decay accelerating factor for complement (Cromer blood group) CD55 antigen DAF CD55 TC Cromer blood group antigen

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08174

part of

Sushi/SCR/CCP superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08174

Sushi/SCR/CCP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08174

encoded by

CD55

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08174

molecular function

virus receptor activity

determination method

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

retrieved

8 April 2019

stated in

Decay-accelerating factor CD55 is identified as the receptor for echovirus 7 using CELICS, a rapid immuno-focal cloning method

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF)

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IPI

lipid binding

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

CD55/decay accelerating factor is part of the lipopolysaccharide-induced receptor complex

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

cell component

membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

Golgi membrane

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

plasma membrane

determination method

IDA

TAS

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

retrieved

8 April 2019

stated in

Isolation of a human erythrocyte membrane glycoprotein with decay-accelerating activity for C3 convertases of the complement system

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

integral component of plasma membrane

determination method

TAS

1 reference

retrieved

31 October 2017

stated in

Cloning of decay-accelerating factor suggests novel use of splicing to generate two proteins

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08174&geneProductId=UniProtKB:P08174

determination method

TAS

transport vesicle

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

extracellular region

determination method

TAS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

cell surface

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Effect of glycosylphosphatidylinositol specific phospholipase D gene expression levels on complement mediated killing of leukemic cells in patients with chronic myeloid leukemia

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

membrane raft

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

anchored component of membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

extracellular exosome

determination method

IDA

4 references

retrieved

31 October 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08174&geneProductId=UniProtKB:P08174

determination method

IDA

retrieved

31 October 2017

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08174&geneProductId=UniProtKB:P08174

determination method

IDA

retrieved

31 October 2017

stated in

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08174&geneProductId=UniProtKB:P08174

determination method

IDA

retrieved

31 October 2017

stated in

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08174&geneProductId=UniProtKB:P08174

determination method

IDA

endoplasmic reticulum-Golgi intermediate compartment membrane

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

secretory granule membrane

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

ficolin-1-rich granule membrane

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

extracellular exosome

determination method

HDA

3 references

retrieved

8 April 2019

stated in

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

HDA

retrieved

8 April 2019

stated in

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

HDA

retrieved

8 April 2019

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

HDA

biological process

regulation of lipopolysaccharide-mediated signaling pathway

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

CD55/decay accelerating factor is part of the lipopolysaccharide-induced receptor complex

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

immune system process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

positive regulation of cytosolic calcium ion concentration

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Activation of human monocytes and granulocytes by monoclonal antibodies to glycosylphosphatidylinositol-anchored antigens

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

positive regulation of CD4-positive, alpha-beta T cell proliferation

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Costimulation via CD55 on human CD4+ T cells mediated by CD97

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

respiratory burst

determination method

NAS

1 reference

retrieved

8 April 2019

stated in

Activation of human monocytes and granulocytes by monoclonal antibodies to glycosylphosphatidylinositol-anchored antigens

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

NAS

endoplasmic reticulum to Golgi vesicle-mediated transport

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

positive regulation of CD4-positive, alpha-beta T cell activation

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Costimulation via CD55 on human CD4+ T cells mediated by CD97

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

CD4-positive, alpha-beta T cell cytokine production

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Costimulation via CD55 on human CD4+ T cells mediated by CD97

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

complement activation, classical pathway

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

viral process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

regulation of complement activation

determination method

TAS

1 reference

retrieved

1 January 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

innate immune response

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

viral entry into host cell

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IEA

neutrophil degranulation

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

negative regulation of complement activation

determination method

IDA

IMP

2 references

retrieved

8 April 2019

stated in

CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and Thrombosis.

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IMP

retrieved

8 April 2019

stated in

Isolation of a human erythrocyte membrane glycoprotein with decay-accelerating activity for C3 convertases of the complement system

GOA

curator

UniProt

UniProt protein ID

P08174

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

regulation of complement activation

determination method

IDA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

TAS

retrieved

8 April 2019

stated in

Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

regulation of complement-dependent cytotoxicity

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08174

determination method

IDA

Gene Atlas image

PBB GE CD55 201925 s at fs.png
732 × 530; 11 KB

0 references

has part(s)

sushi/SCR/CCP domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P08174

Identifiers

MeSH descriptor ID

D018958

0 references

RefSeq protein ID

NP_000565

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1604

NP_001108224

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1604

NP_001287831

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1604

NP_001287832

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1604

NP_001287833

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1604

XP_016855956

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

1604

UniProt protein ID

P08174

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P08174

Ensembl protein ID

ENSP00000316333

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000316333

ENSP00000356031

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356031

ENSP00000340631

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000340631

ENSP00000356030

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356030

ENSP00000356034

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000356034

ENSP00000375788

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000375788

ENSP00000495069

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000495069

ENSP00000493859

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000493859

ENSP00000495477

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000495477

ENSP00000495518

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000495518

ENSP00000496251

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000496251

Freebase ID

/m/0fjffm

0 references

Microsoft Academic ID

8487232

0 references

OpenAlex ID

C8487232

1 reference

stated in

OpenAlex

retrieved

26 January 2022

reference URL

https://docs.openalex.org/download-snapshot/snapshot-data-format

PDB structure ID

1H03

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1H04

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1H2P

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1H2Q

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1M11

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1NWV

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1OJV

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1OJW

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1OJY

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1OK1

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1OK2

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1OK3

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1OK9

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1UOT

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

1UPN

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

2C8I

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

2QZD

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

2QZF

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

2QZH

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

3IYP

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

3J24

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

5FOA

1 reference

stated in

UniProt

UniProt protein ID

P08174

retrieved

5 August 2016

language of work or name

English

UMLS CUI

C0108793

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(12 entries)

edit

• arwiki عامل معجل للبلى
• bswiki Cromer sistem antigena
• cswiki Faktor urychlující rozpad
• cywiki CD55
• dewiki Complement Decay Accelerating Factor
• enwiki Decay-accelerating factor
• frwiki Facteur accélérant le déclin
• jawiki 崩壊促進因子
• ruwiki Фактор ускорения распада комплемента
• ukwiki CD55
• zh_yuewiki 衰變加速因子
• zhwiki 衰變加速因子

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q5248822&oldid=2022907376"