Interleukin 2 receptor subunit gamma (Q5153546)

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mammalian protein found in Homo sapiens

p64
common cytokine receptor gamma chain
CD132 antigen
interleukin 2 receptor, gamma
IL-2RG
nonfunctional common cytokine receptor gamma chain
cytokine receptor common subunit gamma
IL-2R subunit gamma
Interleukin-2 receptor subunit gamma
IL2RG
gammaC
IL-2 receptor subunit gamma
Interleukin Receptor Common gamma Subunit

Language	Label	Description	Also known as
English	Interleukin 2 receptor subunit gamma	mammalian protein found in Homo sapiens	p64 common cytokine receptor gamma chain CD132 antigen interleukin 2 receptor, gamma IL-2RG nonfunctional common cytokine receptor gamma chain cytokine receptor common subunit gamma IL-2R subunit gamma Interleukin-2 receptor subunit gamma IL2RG gammaC IL-2 receptor subunit gamma Interleukin Receptor Common gamma Subunit

Statements

1 reference

13 November 2019

UniProt protein ID

Fibronectin type III superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31785

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31785

Fibronectin type III, protein family

1 reference

based on heuristic

inferred from protein domain or family

Type I cytokine receptor, cytokine-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Short hematopoietin receptor, family 1, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

interleukin-7 receptor activity

determination method

1 reference

8 April 2019

Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

interleukin-2 receptor activity

determination method

1 reference

8 April 2019

Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

protein binding

determination method

3 references

8 April 2019

Human IL-21 and IL-4 bind to partially overlapping epitopes of common gamma-chain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

8 April 2019

Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

cytokine receptor activity

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

interleukin-4 receptor activity

determination method

1 reference

8 April 2019

Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

interleukin-2 binding

determination method

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

cytokine binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

interleukin-15 receptor activity

determination method

1 reference

8 April 2019

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

determination method

3 references

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

31 October 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

plasma membrane

determination method

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

Characterization of the human interleukin-2 receptor gamma chain gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

external side of plasma membrane

determination method

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

determination method

1 reference

14 January 2019

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

determination method

receptor complex

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

plasma membrane

determination method

2 references

biological process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

immune response

determination method

1 reference

8 April 2019

Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

signal transduction

determination method

1 reference

8 April 2019

Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

interleukin-2-mediated signaling pathway

determination method

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

interleukin-4-mediated signaling pathway

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

interleukin-7-mediated signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

interleukin-15-mediated signaling pathway

determination method

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

interleukin-9-mediated signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

regulation of molecular function

determination method

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31785&geneProductId=UniProtKB:P31785

determination method

cytokine-mediated signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

interleukin-2-mediated signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

interleukin-21-mediated signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

positive regulation of phagocytosis

determination method

1 reference

8 April 2019

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31785

determination method

physically interacts with

denileukin diftitox

object has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201550

Gene Atlas image

PBB GE IL2RG 204116 at fs.png
732 × 530; 10 KB

0 references

http://purl.uniprot.org/uniprot/P31785

1 reference

Identifiers.org

Short hematopoietin receptor, family 1, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31785

fibronectin type III

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31785

Type I cytokine receptor, cytokine-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31785

Identifiers

MeSH descriptor ID

subject named as

Interleukin Receptor Common gamma Subunit

0 references

D12.776.543.750.705.852.420.320.875

0 references

D12.776.543.750.705.852.420.360.300.500

0 references

D12.776.543.750.705.852.420.420.500

0 references

D12.776.543.750.705.852.420.500.500

0 references

D12.776.543.750.705.852.420.800.750

0 references

D12.776.543.750.705.852.420.900.500

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000363318

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000363318

ENSP00000388967

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000388967

ENSP00000363303

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000363303

ENSP00000421262

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000421262

ENSP00000423601

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000423601

ENSP00000425233

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000425233

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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