[HSP90 inhibitor 17-AAG plays an important role in JAK3/STAT5 signaling pathways in HTLV-1 infection cell line HUT-102]. (Q49716112)

22 February 2018

title

[HSP90 inhibitor 17-AAG plays an important role in JAK3/STAT5 signaling pathways in HTLV-1 infection cell line HUT-102]. (English)

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22 February 2018

Human T-lymphotropic virus 1

main subject

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Q Q Yang

1

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22 February 2018

H Tan

2

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22 February 2018

Z P Fu

3

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22 February 2018

Q Ma

4

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22 February 2018

J L Song

5

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22 February 2018

language of work or name

Chinese

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publication date

1 August 2017

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22 February 2018

Chinese Journal of Hematology

published in

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22 February 2018

volume

38

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22 February 2018

issue

8

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22 February 2018

page(s)

710-715

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22 February 2018

HSP90 and the chaperoning of cancer

cites work

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12 December 2020

Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.

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12 December 2020

Multiple viral strategies of HTLV-1 for dysregulation of cell growth control

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12 December 2020

HSP-molecular chaperones in cancer biogenesis and tumor therapy: an overview

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12 December 2020

17-Allylamino-17-demethoxygeldanamycin (17-AAG) is effective in down-regulating mutated, constitutively activated KIT protein in human mast cells

1 reference

12 December 2020

Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation.

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12 December 2020

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

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12 December 2020

Co-treatment with heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG) and vorinostat: a highly active combination against human mantle cell lymphoma (MCL) cells

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12 December 2020

Dual role of heat shock proteins as regulators of apoptosis and innate immunity

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12 December 2020

Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL)

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12 December 2020

Hsp90 inhibitors as anti-cancer agents, from basic discoveries to clinical development

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12 December 2020

A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group Study 9303.

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12 December 2020

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.

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12 December 2020

Mechanisms of Jak/STAT signaling in immunity and disease

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12 December 2020

HSP90 inhibitors for cancer therapy and overcoming drug resistance

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12 December 2020

Interleukin-2 and STAT5 in regulatory T cell development and function

1 reference

12 December 2020

Stress-induced inhibition of the NF-kappaB signaling pathway results from the insolubilization of the IkappaB kinase complex following its dissociation from heat shock protein 90.

1 reference

12 December 2020

Ubiquitination and proteasomal degradation of nucleophosmin-anaplastic lymphoma kinase induced by 17-allylamino-demethoxygeldanamycin: role of the co-chaperone carboxyl heat shock protein 70-interacting protein

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12 December 2020

Crystal structure and molecular modeling of 17-DMAG in complex with human Hsp90

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12 December 2020

IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.

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12 December 2020

HSP90 is essential for Jak-STAT signaling in classical Hodgkin lymphoma cells

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12 December 2020

FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases.

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12 December 2020

The Hsp90 molecular chaperone: an open and shut case for treatment

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12 December 2020

Hormone-refractory breast cancer remains sensitive to the antitumor activity of heat shock protein 90 inhibitors.

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12 December 2020

Heat shock protein 90 inhibition depletes TrkA levels and signaling in human acute leukemia cells

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12 December 2020

Evolution of JAK-STAT pathway components: mechanisms and role in immune system development

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12 December 2020

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12 December 2020

Development and application of Hsp90 inhibitors

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12 December 2020

10.3760/CMA.J.ISSN.0253-2727.2017.08.012

Identifiers

DOI

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22 February 2018

PubMed ID

28954352

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22 February 2018