Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis (Q47069226)

4 January 2018

title

Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis (English)

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4 January 2018

Checkpoint protein CELE_H26D21.1

main subject

Caenorhabditis elegans

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Transcription factor cep-1 CELE_F52B5.5

GOA release 2020-03-11

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GOA release 2020-03-11

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7

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4 January 2018

Michael Otmar Hengartner

object named as

Michael O Hengartner

9

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Marc Vidal

8

object named as

Marc Vidal

1 reference

4 January 2018

author name string

E Randal Hofmann

1

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4 January 2018

Stuart Milstein

2

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4 January 2018

Simon J Boulton

3

1 reference

4 January 2018

Mianjia Ye

4

1 reference

4 January 2018

Jen J Hofmann

5

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4 January 2018

Lilli Stergiou

6

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4 January 2018

language of work or name

English

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publication date

1 November 2002

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4 January 2018

published in

Current Biology

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4 January 2018

volume

12

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4 January 2018

issue

22

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4 January 2018

page(s)

1908-1918

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4 January 2018

Genome maintenance mechanisms for preventing cancer

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Stem cells: the intestinal stem cell as a paradigm.

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DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts

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The Schizosaccharomyces pombe rad3 checkpoint gene

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A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans

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DNA-damage-induced checkpoint pathways in the nematode Caenorhabditis elegans

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C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

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7 January 2021

Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.

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7 January 2021

The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis

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7 January 2021

Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes

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7 January 2021

Combined functional genomic maps of the C. elegans DNA damage response

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7 January 2021

Characterization of Schizosaccharomyces pombe Hus1: a PCNA-related protein that associates with Rad1 and Rad9

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7 January 2021

Structure-function analysis of fission yeast Hus1-Rad1-Rad9 checkpoint complex

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7 January 2021

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

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7 January 2021

Hyper-resistance of meiotic cells to radiation due to a strong expression of a single recA-like gene in Caenorhabditis elegans

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7 January 2021

C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpoint

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7 January 2021

MRT-2 checkpoint protein is required for germline immortality and telomere replication in C. elegans

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7 January 2021

Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae

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7 January 2021

Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae

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7 January 2021

The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene

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7 January 2021

CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans

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7 January 2021

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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7 January 2021

Regulation of telomere length by checkpoint genes in Schizosaccharomyces pombe

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7 January 2021

Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

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7 January 2021

CDC-25.1 regulates germline proliferation in Caenorhabditis elegans

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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PUMA, a novel proapoptotic gene, is induced by p53

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7 January 2021

PUMA induces the rapid apoptosis of colorectal cancer cells

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7 January 2021

Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways.

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7 January 2021

Hus1 acts upstream of chk1 in a mammalian DNA damage response pathway

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7 January 2021

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

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7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

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7 January 2021

Reverse genetics by chemical mutagenesis in Caenorhabditis elegans

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7 January 2021

10.1016/S0960-9822(02)01262-9

Identifiers

DOI

1 reference

4 January 2018

release_yk3adwx3pncthinjde3xe6llbq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yk3adwx3pncthinjde3xe6llbq

24 November 2022

mapped directly with Wikidata item

PubMed ID

12445383

1 reference

4 January 2018