Role of the AKT kinase in expansion of multiple myeloma clones: effects on cytokine-dependent proliferative and survival responses (Q45714304)

15 December 2017

Role of the AKT kinase in expansion of multiple myeloma clones: effects on cytokine-dependent proliferative and survival responses (English)

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15 December 2017

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Jung-hsin Hsu

1

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15 December 2017

Yijiang Shi

2

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15 December 2017

Liping Hu

3

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15 December 2017

Myrna Fisher

4

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15 December 2017

Thomas F Franke

5

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15 December 2017

Alan Lichtenstein

6

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15 December 2017

language of work or name

English

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publication date

1 February 2002

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15 December 2017

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15 December 2017

21

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15 December 2017

9

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15 December 2017

1391-1400

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205194

15 December 2017

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cites work

Role of translocation in the activation and function of protein kinase B

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

The akt kinase: molecular determinants of oncogenicity

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

In vitro cytoreductive effects on multiple myeloma cells induced by bisphosphonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Biphasic activation of p21ras by endothelin-1 sequentially activates the ERK cascade and phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

A simplified system for generating recombinant adenoviruses

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Interleukin 6 is essential for in vivo development of B lineage neoplasms

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Vav is associated with signal transducing molecules gp130, Grb2 and Erk2, and is tyrosine phosphorylated in response to interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the AKT2 locus in human pancreatic cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Role of the vav proto-oncogene product (Vav) in erythropoietin-mediated cell proliferation and phosphatidylinositol 3-kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Interleukin 3-dependent survival by the Akt protein kinase

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

7 January 2021

Akt signaling: linking membrane events to life and death decisions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

7 January 2021

Interleukin-6 inhibits apoptosis of malignant plasma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

7 January 2021

Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205194

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205194

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Dimensions Publication ID

15 December 2017

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