Implications for the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with the C. elegans longevity paradigm (Q44000418)

28 November 2017

Implications for the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with the C. elegans longevity paradigm (English)

1 reference

28 November 2017

Caenorhabditis elegans

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1 reference

Ching-Chyuan Hsieh

1

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28 November 2017

James H DeFord

2

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28 November 2017

Kevin Flurkey

3

1 reference

28 November 2017

David E Harrison

4

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28 November 2017

John Papaconstantinou

5

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28 November 2017

language of work or name

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1 May 2002

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Mechanisms of Ageing and Development

28 November 2017

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28 November 2017

123

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28 November 2017

9

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28 November 2017

1229-1244

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Neurosecretory control of aging in Caenorhabditis elegans

28 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Does growth hormone prevent or accelerate aging?

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Extending the lifespan of long-lived mice

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Dwarf mice and the ageing process.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

IRS-2 pathways integrate female reproduction and energy homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Compensatory alterations of insulin signal transduction in liver of growth hormone receptor knockout mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Array-based expression analysis of mouse liver genes: effect of age and of the longevity mutant Prop1df

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Insulin-like growth factor (IGF)-I regulates IGF-binding protein-5 gene expression through the phosphatidylinositol 3-kinase, protein kinase B/Akt, and p70 S6 kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

New mouse dw allele: genetic location and effects on lifespan and growth hormone levels

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

The Snell dwarf mutation Pit1(dw) can increase life span in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Structural organization and alternative splicing of the murine phosphoinositide 3-kinase p85 alpha gene

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Insulin/IGF signalling and ageing: seeing the bigger picture

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Genetic pathways that regulate ageing in model organisms

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Genetic analysis of life-span in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Molecular cloning and characterization of a new insulin/IGF-like peptide of the nematode Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

A conserved regulatory system for aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

A C. elegans mutant that lives twice as long as wild type

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Asking the age-old questions

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

NIDDM genes in mice: deleterious synergism by both parental genomes contributes to diabetogenic thresholds

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Role of binding proteins to IRS-1 in insulin signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

The phosphatidylinositol 3-kinase alpha is required for DNA synthesis induced by some, but not all, growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

A function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

The Drosophila insulin receptor contains a novel carboxyl-terminal extension likely to play an important role in signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Oxidative stress, caloric restriction, and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Role of IRS-2 in insulin and cytokine signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Signalling through the insulin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Regulation of C. elegans life-span by insulinlike signaling in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

Mutations in PROP1 cause familial combined pituitary hormone deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2802%2900036-2

7 January 2021

10.1016/S0047-6374(02)00036-2

Identifiers

DOI

1 reference

28 November 2017

1 reference