An oxysterol-derived positive signal for 3-hydroxy- 3-methylglutaryl-CoA reductase degradation in yeast (Q43514099)

24 November 2017

An oxysterol-derived positive signal for 3-hydroxy- 3-methylglutaryl-CoA reductase degradation in yeast (English)

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24 November 2017

1

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24 November 2017

Shan H

2

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24 November 2017

Matsuda SP

series ordinal

3

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24 November 2017

Hampton RY

series ordinal

4

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24 November 2017

language of work or name

English

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publication date

27 December 2000

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

276

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24 November 2017

12

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24 November 2017

8681-8694

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Regulation of the mevalonate pathway

24 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M007888200

Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Partial deletion of membrane-bound domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase eliminates sterol-enhanced degradation and prevents formation of crystalloid endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007888200

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007888200

Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007888200

ER protein quality control and proteasome-mediated protein degradation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007888200

The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Sterols accelerate degradation of hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase encoded by a constitutively expressed cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Sequence determinants for regulated degradation of yeast 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

A 'distributed degron' allows regulated entry into the ER degradation pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007888200

Expression of heterologous genes in Saccharomyces cerevisiae from vectors utilizing the glyceraldehyde-3-phosphate dehydrogenase gene promoter

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007888200

Effect of triparanol and 3beta-(beta-dimethyl-aminoethoxy)-androst-5-en-17-one on growth and non-saponifiable lipids of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a posttranscriptional level

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Effects of a 2,3-oxidosqualene-lanosterol cyclase inhibitor 2,3:22,23-dioxidosqualene and 24,25-epoxycholesterol on the regulation of cholesterol biosynthesis in human hepatoma cell line HepG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Isolation of 2,3;22,23-dioxidosqualene and 24,25-oxidolanosterol from yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Preferential cyclization of 2,3(S):22(S),23-dioxidosqualene by mammalian 2,3-oxidosqualene-lanosterol cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

In vivo examination of membrane protein localization and degradation with green fluorescent protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007888200

Measuring protein degradation with green fluorescent protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M007888200

The mechanism of action of terbinafine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

The gene encoding squalene epoxidase from Saccharomyces cerevisiae: cloning and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Terbinafine: mode of action and properties of the squalene epoxidase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Four major transcriptional responses in the methionine/threonine biosynthetic pathway of Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

The effects of the hypocholesteremic compound 3β-(β-dimethylaminoethoxy)-androst-5-en-17-one on the sterol and steryl ester composition ofSaccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Molecular dissection of the role of the membrane domain in the regulated degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Translocation-arrested apolipoprotein B evades proteasome degradation via a sterol-sensitive block in ubiquitin conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors Unmask Cryptic Regulatory Mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Epoxidation of 2,3-oxidosqualene to 2,3;22,23-squalene dioxide by squalene epoxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

Transcriptional regulation of the MET3 gene of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007888200

21 January 2018

Identifiers

DOI

10.1074/JBC.M007888200

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24 November 2017

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