Merlin neutralizes the inhibitory effect of Mdm2 on p53. (Q42833103)

8 November 2017

Merlin neutralizes the inhibitory effect of Mdm2 on p53. (English)

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8 November 2017

4

Byung Hyune Choi

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8 November 2017

Hongtae Kim

1

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8 November 2017

Noh-Jin Kwak

2

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8 November 2017

Joo Yong Lee

3

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8 November 2017

Young Lim

5

1 reference

8 November 2017

Young Jin Ko

6

1 reference

8 November 2017

Young-Hoon Kim

7

1 reference

8 November 2017

Pil-Woo Huh

8

1 reference

8 November 2017

Kweon-Haeng Lee

9

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8 November 2017

Hyoung Kyun Rha

10

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8 November 2017

Young-Pil Wang

11

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8 November 2017

language of work or name

English

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publication date

16 December 2003

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Journal of Biological Chemistry

8 November 2017

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8 November 2017

279

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8 November 2017

9

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8 November 2017

7812-7818

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A genetic study of type 2 neurofibromatosis in the United Kingdom. I. Prevalence, mutation rate, fitness, and confirmation of maternal transmission effect on severity

8 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Inhibition of NF2-negative and NF2-positive primary human meningioma cell proliferation by overexpression of merlin due to vector-mediated gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Mechanisms of p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Functions of the MDM2 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Mapping of the p53 and mdm-2 interaction domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

The p53-mdm-2 autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

c-Abl neutralizes the inhibitory effect of Mdm2 on p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Inhibition of NF-kappaB activation by merlin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Liver-specific enhancer II is the target for the p53-mediated inhibition of hepatitis B viral gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Selective transcriptional regulations in the human liver cell by hepatitis B viral X protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Protein 4.1 tumor suppressors: getting a FERM grip on growth regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305526200

21 January 2018

Identifiers

DOI

10.1074/JBC.M305526200

1 reference

8 November 2017

1 reference