Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation (Q42705161)

5 November 2017

Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation (English)

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5 November 2017

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Cristina Ivan

7

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Yoseph Barash

9

object named as

Yoseph Barash

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5 November 2017

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Milan Radovich

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5 November 2017

Lauren K Brady

1

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5 November 2017

Hejia Wang

2

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5 November 2017

Caleb M Radens

3

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5 November 2017

Yue Bi

4

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5 November 2017

Amit Maity

6

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5 November 2017

Mircea Ivan

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5 November 2017

Constantinos Koumenis

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5 November 2017

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English

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publication date

29 September 2017

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5 November 2017

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5 November 2017

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5 November 2017

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5 November 2017

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Creative Commons Attribution 4.0 International

5 November 2017

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29 September 2017

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ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5636171/fullTextXML

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AMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor-Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer Treatment

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Suppression of miR-199a maturation by HuR is crucial for hypoxia-induced glycolytic switch in hepatocellular carcinoma

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27 May 2018

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Increased Serine-Arginine (SR) Protein Phosphorylation Changes Pre-mRNA Splicing in Hypoxia

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27 May 2018

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Widespread intron retention in mammals functionally tunes transcriptomes

27 May 2018

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Hypoxia regulates alternative splicing of HIF and non-HIF target genes.

27 May 2018

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HIFs enhance the transcriptional activation and splicing of adrenomedullin

27 May 2018

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27 May 2018

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HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia

27 May 2018

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CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction

27 May 2018

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DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation.

27 May 2018

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27 May 2018

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Hypoxic regulation of mRNA expression.

27 May 2018

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Hypoxic inhibition of nonsense-mediated RNA decay regulates gene expression and the integrated stress response

27 May 2018

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27 May 2018

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Sequence features responsible for intron retention in human

27 May 2018

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A microRNA signature of hypoxia

27 May 2018

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Alternative splicing: new insights from global analyses

27 May 2018

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Low oxygen stimulates the intellect. Symposium on hypoxia and development, physiology and disease

27 May 2018

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Linking splicing to Pol II transcription stabilizes pre-mRNAs and influences splicing patterns

27 May 2018

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A class of human exons with predicted distant branch points revealed by analysis of AG dinucleotide exclusion zones

27 May 2018

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Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

27 May 2018

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Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

27 May 2018

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The polypyrimidine tract-binding protein stimulates HIF-1alpha IRES-mediated translation during hypoxia

27 May 2018

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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

27 May 2018

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Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing

27 May 2018

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Defective translational control facilitates vesicular stomatitis virus oncolysis

27 May 2018

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A slow RNA polymerase II affects alternative splicing in vivo

27 May 2018

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Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

27 May 2018

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Hypoxia--a key regulatory factor in tumour growth

27 May 2018

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Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

27 May 2018

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Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formation

27 May 2018

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Cap-independent polysomal association of natural mRNAs encoding c-myc, BiP, and eIF4G conferred by internal ribosome entry sites

27 May 2018

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Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

27 May 2018

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Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2-(2-nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-pentafluoropropyl) acetamide].

27 May 2018

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Purification and characterization of the Upf1 protein: a factor involved in translation and mRNA degradation

27 May 2018

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Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation.

27 May 2018

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Prognostic value of tumour blood flow, [¹⁸F]EF5 and [¹⁸F]FDG PET/CT imaging in patients with head and neck cancer treated with radiochemotherapy.

16 August 2018

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Orchestrated intron retention regulates normal granulocyte differentiation.

16 August 2018

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Alternative splicing regulates biogenesis of miRNAs located across exon-intron junctions

16 August 2018

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Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study

16 August 2018

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Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals.

16 August 2018

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Widespread predicted nonsense-mediated mRNA decay of alternatively-spliced transcripts of human normal and disease genes

16 August 2018

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Differential GC Content between Exons and Introns Establishes Distinct Strategies of Splice-Site Recognition

16 August 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2002623

Relation of a Hypoxia Metagene Derived from Head and Neck Cancer to Prognosis of Multiple Cancers

21 January 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.2002623

Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28961236

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PBIO.2002623

1 reference

5 November 2017

1 reference

5 November 2017

1 reference