Bone morphogenetic protein 1 (Q426782)

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mammalian protein found in Homo sapiens

• mTld
• bone morphogenetic protein 1
• BMP1
• mammalian tolloid protein
• procollagen C-proteinase 3
• Procollagen C-proteinase
• PCP
• procollagen C-endopeptidase
• tolloid-like

edit

Language	Label	Description	Also known as
English	Bone morphogenetic protein 1	mammalian protein found in Homo sapiens	mTld bone morphogenetic protein 1 BMP1 mammalian tolloid protein procollagen C-proteinase 3 Procollagen C-proteinase PCP procollagen C-endopeptidase tolloid-like

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13497

secreted matrix metalloproteinases

0 references

tolloid-like metalloproteinases

0 references

bone morphogenetic protein

0 references

part of

Spermadhesin, CUB domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

Bone morphogenetic protein 1/tolloid-like protein

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

Metallopeptidase, catalytic domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

Growth factor receptor cysteine-rich domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

CUB domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase, metallopeptidase family

1 reference

based on heuristic

inferred from protein domain or family

Tolloid/BMP1 peptidase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase M12A family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like calcium-binding, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13497

encoded by

BMP1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13497

molecular function

calcium ion binding

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

zinc ion binding

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

metal ion binding

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

peptidase activity

determination method

IDA

IEA

TAS

4 references

retrieved

9 May 2019

stated in

Bone morphogenetic protein-1: the type I procollagen C-proteinase

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

TAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

retrieved

9 May 2019

stated in

bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axis

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IDA

retrieved

9 May 2019

stated in

PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IDA

protein binding

determination method

IPI

6 references

retrieved

9 May 2019

stated in

Identification of binding partners interacting with the α1-N-propeptide of type V collagen

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IPI

retrieved

9 May 2019

stated in

K153R polymorphism in myostatin gene increases the rate of promyostatin activation by furin

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IPI

retrieved

9 May 2019

stated in

Role of dimerization and substrate exclusion in the regulation of bone morphogenetic protein-1 and mammalian tolloid

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IPI

retrieved

9 May 2019

stated in

Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IPI

retrieved

9 May 2019

stated in

Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IPI

retrieved

9 May 2019

stated in

Role of the netrin-like domain of procollagen C-proteinase enhancer-1 in the control of metalloproteinase activity

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IPI

metalloendopeptidase activity

determination method

TAS

IEA

3 references

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13497&geneProductId=UniProtKB:P13497

determination method

TAS

retrieved

7 November 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13497&geneProductId=UniProtKB:P13497

determination method

IEA

retrieved

7 November 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13497&geneProductId=UniProtKB:P13497

determination method

IEA

growth factor activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

hydrolase activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

metallopeptidase activity

determination method

NAS

IEA

3 references

retrieved

9 May 2019

stated in

Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

NAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

serine-type endopeptidase activity

determination method

TAS

1 reference

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P13497&geneProductId=UniProtKB:P13497

determination method

TAS

cytokine activity

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

identical protein binding

determination method

IPI

1 reference

retrieved

9 May 2019

stated in

Role of dimerization and substrate exclusion in the regulation of bone morphogenetic protein-1 and mammalian tolloid

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IPI

metalloendopeptidase activity

determination method

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

cell component

Golgi apparatus

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

extracellular region

determination method

TAS

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

TAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

vesicle

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

extracellular space

determination method

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

biological process

skeletal system development

determination method

NAS

TAS

2 references

retrieved

9 May 2019

stated in

Novel regulators of bone formation: molecular clones and activities

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

TAS

retrieved

9 May 2019

stated in

Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

NAS

cell differentiation

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

ossification

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

extracellular matrix disassembly

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

TAS

proteolysis

determination method

IDA

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

retrieved

9 May 2019

stated in

bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axis

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IDA

multicellular organism development

determination method

TAS

IEA

2 references

retrieved

9 May 2019

stated in

Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

TAS

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

cartilage development

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P13497

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

positive regulation of cartilage development

determination method

IDA

1 reference

retrieved

9 May 2019

stated in

Novel regulators of bone formation: molecular clones and activities

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IDA

cartilage condensation

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

Novel regulators of bone formation: molecular clones and activities

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

TAS

high-density lipoprotein particle assembly

determination method

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

TAS

regulation of signaling receptor activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

signal transduction

determination method

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13497

determination method

IEA

Gene Atlas image

PBB GE BMP1 207595 s at fs.png
732 × 530; 11 KB

0 references

exact match

http://purl.uniprot.org/uniprot/P13497

1 reference

stated in

Identifiers.org

has part(s)

Peptidase M12A domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

CUB domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

EGF-type aspartate/asparagine hydroxylation site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

EGF-like calcium-binding domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

EGF-like, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

EGF-like calcium-binding, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

EGF-like domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

Peptidase, metallopeptidase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

Tolloid/BMP1 peptidase domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P13497

Identifiers

MeSH descriptor ID

D055395

subject named as

Bone Morphogenetic Protein 1

0 references

MeSH tree code

D08.811.277.656.300.480.525.700.049

0 references

D08.811.277.656.675.374.525.700.900.500

0 references

D12.644.276.848.049

0 references

D12.644.276.948.500

0 references

D12.644.276.954.200.100

0 references

D12.776.467.836.049

0 references

D12.776.467.942.200.100

0 references

D12.776.467.948.500

0 references

D23.529.942.200.100

0 references

D23.529.948.500

0 references

RefSeq protein ID

NP_001190

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

649

NP_006120

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

649

UniProt protein ID

P13497

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P13497

Ensembl protein ID

ENSP00000305714

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000305714

ENSP00000306121

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000306121

ENSP00000428332

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000428332

ENSP00000428665

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000428665

ENSP00000430406

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000430406

ENSP00000346941

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000346941

ENSP00000380915

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000380915

ENSP00000427950

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000427950

ENSP00000428249

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000428249

ENSP00000428798

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000428798

ENSP00000430015

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000430015

ENSP00000430977

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000430977

Freebase ID

/m/0dy6n3

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

170794382

0 references

PDB structure ID

3EDG

1 reference

stated in

UniProt

UniProt protein ID

P13497

retrieved

4 August 2016

language of work or name

English

3EDH

1 reference

stated in

UniProt

UniProt protein ID

P13497

retrieved

4 August 2016

language of work or name

English

UMLS CUI

C0377148

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(6 entries)

edit

• bswiki Koštanomorfogenetski protein 1
• cywiki BMP1
• dewiki Knochenmorphogenetisches Protein 1
• enwiki Bone morphogenetic protein 1
• idwiki Protein BM-1
• ukwiki BMP1

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q426782&oldid=2022902424"