microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer's disease triple transgenic mice (Q42384091)

29 October 2017

microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer's disease triple transgenic mice (English)

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29 October 2017

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7

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29 October 2017

Sébastien S Hébert

12

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Frédéric Calon

10

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29 October 2017

author name string

Julia Hernandez-Rapp

1

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29 October 2017

Sara Rainone

2

1 reference

29 October 2017

Claudia Goupil

3

1 reference

29 October 2017

Véronique Dorval

4

1 reference

29 October 2017

Pascal Y Smith

5

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29 October 2017

Martine Saint-Pierre

6

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29 October 2017

Emmanuel Planel

8

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29 October 2017

Arnaud Droit

9

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29 October 2017

Francesca Cicchetti

11

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29 October 2017

language of work or name

English

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publication date

3 August 2016

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29 October 2017

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29 October 2017

6

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29 October 2017

30953

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Creative Commons Attribution 4.0 International

29 October 2017

start time

3 August 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4971468/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/srep30953

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cites work

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Cortical Amyloid Burden Differences Across Empirically-Derived Mild Cognitive Impairment Subtypes and Interaction with APOE ɛ4 Genotype

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MicroRNA-132 and early growth response-1 in nucleus basalis of Meynert during the course of Alzheimer's disease

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Targeted deletion of miR-132/-212 impairs memory and alters the hippocampal transcriptome

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Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure

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Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment

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Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease

28 May 2018

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miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.

28 May 2018

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An allelic series of miR-17 ∼ 92-mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron

28 May 2018

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Mutation in the 3'untranslated region of APP as a genetic determinant of cerebral amyloid angiopathy

28 May 2018

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SIRT1 in the brain-connections with aging-associated disorders and lifespan

28 May 2018

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Re-thinking miRNA-mRNA interactions: intertwining issues confound target discovery

28 May 2018

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MicroRNA landscape in Alzheimer's disease

28 May 2018

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The biological functions of miRNAs: lessons from in vivo studies

28 May 2018

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mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues

28 May 2018

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A novel microRNA-132-sirtuin-1 axis underlies aberrant B-cell cytokine regulation in patients with relapsing-remitting multiple sclerosis [corrected].

28 May 2018

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Regulation of microRNA biogenesis

28 May 2018

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Cilostazol suppresses β-amyloid production by activating a disintegrin and metalloproteinase 10 via the upregulation of SIRT1-coupled retinoic acid receptor-β.

28 May 2018

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Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway

28 May 2018

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Trimmomatic: a flexible trimmer for Illumina sequence data

28 May 2018

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Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence

28 May 2018

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Alteration of the microRNA network during the progression of Alzheimer's disease

28 May 2018

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Adult-specific functions of animal microRNAs

28 May 2018

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SIRT1 and SIRT2: emerging targets in neurodegeneration

28 May 2018

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A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls.

28 May 2018

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28 May 2018

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The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.

28 May 2018

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miR-212/132 expression and functions: within and beyond the neuronal compartment

28 May 2018

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Leptin boosts cellular metabolism by activating AMPK and the sirtuins to reduce tau phosphorylation and β-amyloid in neurons

28 May 2018

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Molecular network of microRNA targets in Alzheimer's disease brains

28 May 2018

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MicroRNAs and Alzheimer's Disease Mouse Models: Current Insights and Future Research Avenues

28 May 2018

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MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy.

28 May 2018

1 reference

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microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Acetylation of tau inhibits its degradation and contributes to tauopathy

28 May 2018

1 reference

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Transcriptome profiling in neurodegenerative disease.

28 May 2018

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Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

MEK inhibitors suppress beta-amyloid production by altering the level of a beta-C-terminal fragment of amyloid precursor protein in neuronal cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

MAPK, beta-amyloid and synaptic dysfunction: the role of RAGE.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

MicroRNA 132 regulates nutritional stress-induced chemokine production through repression of SirT1

28 May 2018

1 reference

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Recent insights into the molecular genetics of dementia

28 May 2018

1 reference

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Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps

28 May 2018

1 reference

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ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

28 May 2018

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TopHat: discovering splice junctions with RNA-Seq

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Alterations of the microRNA network cause neurodegenerative disease.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

MicroRNA regulation of Alzheimer's Amyloid precursor protein expression.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Widespread changes in protein synthesis induced by microRNAs

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

The impact of microRNAs on protein output

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Tau is essential to beta -amyloid-induced neurotoxicity

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Memory formation and retention are affected in adult miR-132/212 knockout mice.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Serum miR-206 and miR-132 as Potential Circulating Biomarkers for Mild Cognitive Impairment.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

A self-organizing miR-132/Ctbp2 circuit regulates bimodal notch signals and glial progenitor fate choice during spinal cord maturation

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

MiR-132 inhibits expression of SIRT1 and induces pro-inflammatory processes of vascular endothelial inflammation through blockade of the SREBP-1c metabolic pathway

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

The Effects of SIRT1 on Alzheimer's Disease Models

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

Decreased drebrin mRNA expression in Alzheimer disease: correlation with tau pathology.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4971468

16 August 2018

Identifiers

DOI

10.1038/SREP30953

1 reference

29 October 2017

1 reference

29 October 2017

1 reference