integrin subunit alpha 4 (Q4201951)

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mammalian protein found in Homo sapiens
  • 269C wild type
  • integrin alpha-IV
  • CD49 antigen-like family member D
  • very late activation protein 4 receptor, alpha 4 subunit
  • alpha 4 subunit of VLA-4 receptor
  • antigen CD49D, alpha-4 subunit of VLA-4 receptor
  • VLA-4 subunit alpha
  • integrin alpha-4
  • ITGA4
  • Integrin alpha4
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Language Label Description Also known as
English
integrin subunit alpha 4
mammalian protein found in Homo sapiens
  • 269C wild type
  • integrin alpha-IV
  • CD49 antigen-like family member D
  • very late activation protein 4 receptor, alpha 4 subunit
  • alpha 4 subunit of VLA-4 receptor
  • antigen CD49D, alpha-4 subunit of VLA-4 receptor
  • VLA-4 subunit alpha
  • integrin alpha-4
  • ITGA4
  • Integrin alpha4

Statements

molecular function
protein binding
determination method
IPI
9 references
retrieved
8 April 2019
stated in
Propolypeptide of von Willebrand factor is a novel ligand for very late antigen-4 integrin
GOA
curator
UniProt
UniProt protein ID
P13612
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IPI
retrieved
8 April 2019
stated in
alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor
GOA
curator
UniProt
UniProt protein ID
P13612
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IPI
retrieved
8 April 2019
stated in
Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IPI
retrieved
8 April 2019
stated in
A family of beta 7 integrins on human mucosal lymphocytes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IPI
retrieved
8 April 2019
stated in
Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IPI
retrieved
8 April 2019
stated in
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesion
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IPI
retrieved
8 April 2019
stated in
Matrix metalloproteinase-9 promotes chronic lymphocytic leukemia b cell survival through its hemopexin domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IPI
retrieved
8 April 2019
stated in
Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IPI
retrieved
8 April 2019
stated in
Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IPI
cell component
cell surface
determination method
IDA
IEA
5 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IEA
retrieved
8 April 2019
stated in
Disruption of disulfide restriction at integrin knees induces activation and ligand-independent signaling of α₄β₇
GOA
curator
UniProt
UniProt protein ID
P13612
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IDA
retrieved
8 April 2019
stated in
CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow
GOA
curator
UniProt
UniProt protein ID
P13612
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IDA
retrieved
8 April 2019
stated in
Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels
GOA
curator
UniProt
UniProt protein ID
P13612
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IDA
retrieved
8 April 2019
stated in
Vascular cell adhesion molecule-1 and the integrin VLA-4 mediate adhesion of human B cell precursors to cultured bone marrow adherent cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13612
determination method
IDA
biological process
Gene Atlas image
PBB GE ITGA4 213416 at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
D039441
subject named as
Integrin alpha4
0 references
 
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