Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration. (Q41791633)

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6 January 2020

title

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration (English)

1 reference

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Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

6 January 2020

main subject

endothelium

0 references

1 reference

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

GOA release 2020-03-11

1 reference

Phosphoinositide-3-kinase regulatory subunit 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Julie Guillermet-Guibert

2

1 reference

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6 January 2020

Anne Ridley

12

1 reference

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6 January 2020

Christiana Ruhrberg

13

1 reference

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6 January 2020

Mariona Graupera

1

1 reference

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6 January 2020

Jaime Millán

9

1 reference

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6 January 2020

Holger Gerhardt

14

1 reference

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6 January 2020

Holger Gerhardt

15

1 reference

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6 January 2020

16

Bart Vanhaesebroeck

1 reference

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6 January 2020

author name string

Lazaros C Foukas

3

1 reference

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6 January 2020

Li-Kun Phng

4

1 reference

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6 January 2020

Robert J Cain

5

1 reference

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6 January 2020

Ashreena Salpekar

6

1 reference

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6 January 2020

Wayne Pearce

7

1 reference

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6 January 2020

Stephen Meek

8

1 reference

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6 January 2020

Andrew J H Smith

11

1 reference

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6 January 2020

Pedro R Cutillas

10

1 reference

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6 January 2020

language of work or name

English

0 references

publication date

30 April 2008

1 reference

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6 January 2020

1 reference

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6 January 2020

volume

453

1 reference

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6 January 2020

issue

7195

1 reference

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6 January 2020

page(s)

662-666

1 reference

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https://scigraph.springernature.com/pub.10.1038/nature06892

6 January 2020

exact match

0 references

cites work

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

A specific antagonist of the p110delta catalytic component of phosphatidylinositol 3'-kinase, IC486068, enhances radiation-induced tumor vascular destruction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Mechanisms and implications of phosphoinositide 3-kinase delta in promoting neutrophil trafficking into inflamed tissue.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

p110δ, a novel phosphoinositide 3-kinase in leukocytes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

p110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Deficiency in the p110alpha subunit of PI3K results in diminished Tie2 expression and Tie2(-/-)-like vascular defects in mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Vascular remodeling of the mouse yolk sac requires hemodynamic force

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Identification of tyrosine residues in vascular endothelial growth factor receptor-2/FLK-1 involved in activation of phosphatidylinositol 3-kinase and cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

RhoB controls Akt trafficking and stage-specific survival of endothelial cells during vascular development

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

RhoA is required for monocyte tail retraction during transendothelial migration

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Roles of endothelial cell migration and apoptosis in vascular remodeling during development of the central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Conditional immortalization of growth factor-responsive cardiac endothelial cells from H-2K(b)-tsA58 mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Determination of GTP loading on Rho

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06892

7 January 2021

Identifiers

DOI

10.1038/NATURE06892

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18449193%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 January 2020

0 references

1 reference