Dbl family proteins (Q41374941)

30 September 2017

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title

Dbl family proteins (English)

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30 September 2017

I P Whitehead

1

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30 September 2017

S Campbell

series ordinal

2

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30 September 2017

K L Rossman

series ordinal

3

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30 September 2017

C J Der

series ordinal

4

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30 September 2017

1 February 1997

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Biochimica et Biophysica Acta

30 September 2017

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30 September 2017

1332

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30 September 2017

1

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30 September 2017

F1-23

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The GTPase superfamily: conserved structure and molecular mechanism

30 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Proteins regulating Ras and its relatives

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

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https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Function and regulation of ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

1 reference

7 January 2021

The Ras signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The hunt for Ras targets

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https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

A role for Rho in Ras transformation

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https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The GTPase superfamily: a conserved switch for diverse cell functions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The ras protein family: evolutionary tree and role of conserved amino acids

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

1 reference

7 January 2021

Membrane ruffling and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Small GTP-binding proteins and the regulation of the actin cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Direct involvement of the small GTP-binding protein Rho in lbc oncogene function

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

A role for Rac in Tiam1-induced membrane ruffling and invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Development of cell polarity in budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Isolation of a new human oncogene from a diffuse B-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Roles of the CDC24 gene product in cellular morphogenesis during the Saccharomyces cerevisiae cell cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Cooperative interaction of S. pombe proteins required for mating and morphogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Oncogene ect2 is related to regulators of small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Reduced hormone-stimulated adenylate cyclase activity in NIH-3T3 cells expressing the EJ human bladder ras oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

A tumor-specific membrane phosphoprotein marker in human cell hybrids

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Unique fusion of bcr and c-abl genes in Philadelphia chromosome positive acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The BCR gene encodes a novel serine/threonine kinase activity within a single exon

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Genetic evidence for the roles of the bud-site-selection genes BUD5 and BUD2 in control of the Rsr1p (Bud1p) GTPase in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Complex formation between RAS and RAF and other protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Concerted action of RAS and G proteins in the sexual response pathways of Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The Dbl oncogene product as a GDP/GTP exchange protein for the Rho family: its properties in comparison with those of Smg GDS

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Functional roles for the pleckstrin and Dbl homology regions in the Ras exchange factor Son-of-sevenless

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The PH domain: a common piece in the structural patchwork of signalling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

PH domain: the first anniversary

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Regulated and constitutive activity by CDC25Mm (GRF), a Ras-specific exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Pheromone response in yeast: association of Bem1p with proteins of the MAP kinase cascade and actin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Hematopoietic development of vav-/- mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Increased neutrophil respiratory burst in bcr-null mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Prediction of protein secondary structure at better than 70% accuracy

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Combining evolutionary information and neural networks to predict protein secondary structure

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2896%2900040-6

7 January 2021

10.1016/S0304-419X(96)00040-6

Identifiers

DOI

1 reference

30 September 2017

1 reference