A sequence in the carboxy-terminus of the alpha(1C) subunit important for targeting, conductance and open probability of L-type Ca(2+) channels. (Q40866660)

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scientific article published on July 2000

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English	A sequence in the carboxy-terminus of the alpha(1C) subunit important for targeting, conductance and open probability of L-type Ca(2+) channels.	scientific article published on July 2000

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8 November 2019

A sequence in the carboxy-terminus of the alpha(1C) subunit important for targeting, conductance and open probability of L-type Ca(2+) channels (English)

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8 November 2019

Christoph Romanin

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8 November 2019

Klaus Groschner

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8 November 2019

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K J Kepplinger

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8 November 2019

H Kahr

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8 November 2019

G Förstner

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8 November 2019

M Sonnleitner

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H Schindler

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8 November 2019

T Schmidt

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8 November 2019

N M Soldatov

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1 July 2000

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8 November 2019

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8 November 2019

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8 November 2019

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8 November 2019

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8 November 2019

Calcium and Cardiac Excitation-Contraction Coupling

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L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes

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Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity

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Molecular basis for Ca2+ channel diversity

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Structure and function of voltage-gated ion channels

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Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart

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Molecular structures involved in L-type calcium channel inactivation. Role of the carboxyl-terminal region encoded by exons 40-42 in alpha1C subunit in the kinetics and Ca2+ dependence of inactivation

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Molecular determinants of L-type Ca2+ channel inactivation. Segment exchange analysis of the carboxyl-terminal cytoplasmic motif encoded by exons 40-42 of the human alpha1C subunit gene.

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Molecular diversity of L-type Ca2+ channel transcripts in human fibroblasts

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Genomic structure of human L-type Ca2+ channel

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Calmodulin supports both inactivation and facilitation of L-type calcium channels.

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Ca2+-induced inhibition of the cardiac Ca2+ channel depends on calmodulin

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Different voltage-dependent inhibition by dihydropyridines of human Ca2+ channel splice variants

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Intracellular Ca2+ inactivates L-type Ca2+ channels with a Hill coefficient of approximately 1 and an inhibition constant of approximately 4 microM by reducing channel's open probability

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Trypsin increases availability and open probability of cardiac L-type Ca2+ channels without affecting inactivation induced by Ca2+.

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Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes

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Current modulation and membrane targeting of the calcium channel alpha1C subunit are independent functions of the beta subunit.

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Roles of a membrane-localized beta subunit in the formation and targeting of functional L-type Ca2+ channels

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Multiple modulation pathways of calcium channel activity by a beta subunit. Direct evidence of beta subunit participation in membrane trafficking of the alpha1C subunit

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21 January 2018

Complexes of the alpha1C and beta subunits generate the necessary signal for membrane targeting of class C L-type calcium channels

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Crystal structure of the tetramerization domain of the Shaker potassium channel

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21 January 2018

Ca2+-sensitive inactivation of L-type Ca2+ channels depends on multiple cytoplasmic amino acid sequences of the alpha1C subunit

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21 January 2018

Ca2+ channel sensitivity towards the blocker isradipine is affected by alternative splicing of the human alpha1C subunit gene

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21 January 2018

Involvement of dihydropyridine receptors in excitation–contraction coupling in skeletal muscle

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Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

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21 January 2018

Calmodulin is the Ca2+ sensor for Ca2+ -dependent inactivation of L-type calcium channels

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21 January 2018

Action of calpastatin in prevention of cardiac L-type Ca2+ channel run-down cannot be mimicked by synthetic calpain inhibitors

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Identifiers

10.1016/S0014-5793(00)01791-9

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Europe PubMed Central

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8 November 2019

1 reference

Europe PubMed Central

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8 November 2019

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