p21/CDKN1A mediates negative regulation of transcription by p53. (Q40647697)

22 September 2017

p21/CDKN1A mediates negative regulation of transcription by p53. (English)

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22 September 2017

4

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22 September 2017

Kristina Löhr

1

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22 September 2017

Constanze Möritz

series ordinal

2

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22 September 2017

Ana Contente

series ordinal

3

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22 September 2017

language of work or name

English

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publication date

13 May 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

35

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22 September 2017

32507-32516

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https://api.crossref.org/works/10.1074%2FJBC.M212517200

22 September 2017

1 reference

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Wild-type p53 negatively regulates the expression of a microtubule-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

The corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Pathways governing G1/S transition and their response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

p53 down-regulates CHK1 through p21 and the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

p130/E2F4 binds to and represses the cdc2 promoter in response to p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

p53 regulation of G(2) checkpoint is retinoblastoma protein dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

A simplified system for generating recombinant adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

The nuclear export signal within the E4orf6 protein of adenovirus type 5 supports virus replication and cytoplasmic accumulation of viral mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

A polymorphic microsatellite that mediates induction of PIG3 by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Bak and Bax function to limit adenovirus replication through apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Regulation of the specific DNA binding function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

A model for p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Switching from life to death: the Miz-ing link between Myc and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Mdm2 inhibition of p53 induces E2F1 transactivation via p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Role of the p53-homologue p73 in E2F1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Induction of the growth inhibitor IGF-binding protein 3 by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

P63 and P73: P53 mimics, menaces and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Repression of BRCA1 through a feedback loop involving p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Tumor suppressor p53 is required to modulate BRCA1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

A new model of cell cycle-regulated transcription: repression of the cyclin A promoter by CDF-1 and anti-repression by E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Repression of CDK1 and other genes with CDE and CHR promoter elements during DNA damage-induced G(2)/M arrest in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

DNA Damage Induces p53-dependent Down-regulation of hCHK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

The tumour suppressor protein p53 can repress transcription of cyclin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

p53 regulates a G2 checkpoint through cyclin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

Myc suppression of the p21 Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212517200

21 January 2018

Identifiers

DOI

10.1074/JBC.M212517200

1 reference

22 September 2017

1 reference