3-hydroxyisobutyrate dehydrogenase (Q4042285)

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mammalian protein found in Homo sapiens

• epididymis secretory sperm binding protein
• 3-hydroxyisobutyrate dehydrogenase, mitochondrial
• HIBADH
• 3'-hydroxyisobutyrate dehydrogenase

edit

Language	Label	Description	Also known as
English	3-hydroxyisobutyrate dehydrogenase	mammalian protein found in Homo sapiens	epididymis secretory sperm binding protein 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 3'-hydroxyisobutyrate dehydrogenase

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P31937

part of

6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31937

6-phosphogluconate dehydrogenase, domain 2

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31937

NAD(P)-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31937

3-hydroxyisobutyrate dehydrogenase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31937

3-hydroxyisobutyrate dehydrogenase, NAD-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

6-phosphogluconate dehydrogenase, NADP-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

3-hydroxyisobutyrate dehydrogenase-related, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P31937

encoded by

HIBADH

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P31937

molecular function

3-hydroxyisobutyrate dehydrogenase activity

determination method

IDA

TAS

IEA

4 references

retrieved

21 June 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

TAS

retrieved

21 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

21 June 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

21 June 2018

stated in

Clinical, biochemical, and molecular findings in three patients with 3-hydroxyisobutyric aciduria

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IDA

oxidoreductase activity

determination method

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IEA

NAD binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IEA

phosphogluconate dehydrogenase (decarboxylating) activity

determination method

IEA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IEA

NADP binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IEA

3-hydroxyisobutyrate dehydrogenase activity

determination method

IBA

IDA

IEA

TAS

5 references

retrieved

10 September 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

TAS

retrieved

10 September 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

10 September 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

10 September 2018

stated in

Clinical, biochemical, and molecular findings in three patients with 3-hydroxyisobutyric aciduria

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IDA

retrieved

10 September 2018

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IBA

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IBA

3-hydroxyisobutyrate dehydrogenase activity

determination method

IBA

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

8 April 2019

stated in

Clinical, biochemical, and molecular findings in three patients with 3-hydroxyisobutyric aciduria

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IBA

cell component

mitochondrial matrix

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

TAS

mitochondrion

determination method

IEA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IEA

mitochondrion

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IBA

biological process

valine catabolic process

determination method

IDA

IEA

2 references

retrieved

21 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

21 June 2018

stated in

Clinical, biochemical, and molecular findings in three patients with 3-hydroxyisobutyric aciduria

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31937&geneProductId=UniProtKB:P31937

determination method

IDA

branched-chain amino acid catabolic process

determination method

TAS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IEA

valine catabolic process

determination method

IBA

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IEA

retrieved

8 April 2019

stated in

Clinical, biochemical, and molecular findings in three patients with 3-hydroxyisobutyric aciduria

GOA

curator

UniProt

UniProt protein ID

P31937

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31937

determination method

IBA

EC enzyme number

1.1.1.31

0 references

Gene Atlas image

PBB GE HIBADH gnf1h05976 at fs.png
732 × 530; 11 KB

0 references

has part(s)

3-hydroxyisobutyrate dehydrogenase-related, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31937

3-hydroxyisobutyrate dehydrogenase, NAD-binding domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31937

6-phosphogluconate dehydrogenase, NADP-binding

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P31937

Identifiers

RefSeq protein ID

NP_689953

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

11112

XP_016867208

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

11112

UniProt protein ID

P31937

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P31937

Ensembl protein ID

ENSP00000265395

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000265395

ENSP00000390205

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000390205

ENSP00000393365

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000393365

Freebase ID

/m/03cmrnw

1 reference

stated in

Freebase Data Dumps

publication date

28 October 2013

PDB structure ID

2GF2

1 reference

stated in

UniProt

UniProt protein ID

P31937

retrieved

4 August 2016

language of work or name

English

2I9P

1 reference

stated in

UniProt

UniProt protein ID

P31937

retrieved

4 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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