Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5. (Q39964579)

16 September 2017

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5. (English)

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16 September 2017

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Michael Potente

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Elisabetta Dejana

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Elisabetta Dejana

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Valentina Pirazzoli

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Andrea Taddei

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Costanza Giampietro

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Annarita Conti

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Fabrizio Orsenigo

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Ferruccio Breviario

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Christopher Daly

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6 July 2008

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https://scigraph.springernature.com/pub.10.1038/ncb1752

16 September 2017

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cites work

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7 January 2021

Claudins in occluding junctions of humans and flies

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Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice

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Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization

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Molecular perspective on tight-junction assembly and epithelial polarity

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Cell-junctional and cytoskeletal organization in mouse blastocysts lacking E-cadherin.

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Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin

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Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

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7 January 2021

Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo

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7 January 2021

The multiple languages of endothelial cell-to-cell communication

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Cadherin-mediated cellular signaling

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7 January 2021

Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148

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7 January 2021

Mechanisms of VE-cadherin processing and degradation in microvascular endothelial cells.

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7 January 2021

VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam

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7 January 2021

VE-cadherin is not required for the formation of nascent blood vessels but acts to prevent their disassembly

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7 January 2021

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

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7 January 2021

Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1).

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7 January 2021

Cell cycle and death control: long live Forkheads

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7 January 2021

Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms. Direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding

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FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

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FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

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Autocrine VEGF signaling is required for vascular homeostasis

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Inhibition of multiple vascular endothelial growth factor receptors (VEGFR) blocks lymph node metastases but inhibition of VEGFR-2 is sufficient to sensitize tumor cells to platinum-based chemotherapeutics

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Molecular basis for sunitinib efficacy and future clinical development

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Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

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Functional interaction between beta-catenin and FOXO in oxidative stress signaling

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Wnt/beta-catenin signaling in development and disease

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The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis

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7 January 2021

Regulation of smooth muscle cell proliferation by beta-catenin/T-cell factor signaling involves modulation of cyclin D1 and p21 expression

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7 January 2021

Claudins and epithelial paracellular transport

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7 January 2021

Akt takes center stage in angiogenesis signaling

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7 January 2021

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

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7 January 2021

Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.

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7 January 2021

Regulation of E-cadherin/Catenin association by tyrosine phosphorylation.

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7 January 2021

The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin

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7 January 2021

Downregulation of vascular endothelial-cadherin expression is associated with an increase in vascular tumor growth and hemorrhagic complications

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7 January 2021

The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility

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7 January 2021

A third-generation lentivirus vector with a conditional packaging system

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7 January 2021

Production of high-titer helper-free retroviruses by transient transfection

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7 January 2021

Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis

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7 January 2021

A functional screen in human cells identifies UBF2 as an RNA polymerase II transcription factor that enhances the beta-catenin signaling pathway

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7 January 2021

Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

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7 January 2021

Gene expression analysis of early and advanced gastric cancers.

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7 January 2021

MatInspector and beyond: promoter analysis based on transcription factor binding sites

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7 January 2021

The forkhead transcription factor Foxo1 regulates adipocyte differentiation

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7 January 2021

Identifiers

DOI

10.1038/NCB1752

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16 September 2017

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