CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma (Q37054587)

18 August 2017

CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma (English)

1 reference

18 August 2017

0 references

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9

Matteo Pellegrini

1 reference

18 August 2017

Diana L Moughon

3

0 references

Junhui Hu

object named as

Junhui Hu

2

0 references

author name string

Shiruyeh Schokrpur

1

1 reference

18 August 2017

Peijun Liu

4

1 reference

18 August 2017

Lucia C Lin

5

1 reference

18 August 2017

Kip Hermann

6

1 reference

18 August 2017

Serghei Mangul

7

1 reference

18 August 2017

Wei Guan

8

1 reference

18 August 2017

Hua Xu

10

1 reference

18 August 2017

Lily Wu

11

1 reference

18 August 2017

language of work or name

English

0 references

publication date

30 June 2016

1 reference

18 August 2017

1 reference

18 August 2017

6

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18 August 2017

29032

1 reference

Creative Commons Attribution 4.0 International

18 August 2017

start time

30 June 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/srep29032

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cites work

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29 September 2017

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Combined mutation of Vhl and Trp53 causes renal cysts and tumours in mice

29 September 2017

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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

29 September 2017

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CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Genetic and functional studies implicate HIF1α as a 14q kidney cancer suppressor gene

29 September 2017

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Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors

29 September 2017

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29 September 2017

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29 September 2017

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Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α.

29 September 2017

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EMT: a new vision of hypoxia promoting cancer progression

29 September 2017

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von Hippel-Lindau disease: a clinical and scientific review

29 September 2017

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Tumor biology and prognostic factors in renal cell carcinoma

29 September 2017

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29 September 2017

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NF-kappaB-dependent plasticity of the epithelial to mesenchymal transition induced by Von Hippel-Lindau inactivation in renal cell carcinomas

29 September 2017

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The basics of epithelial-mesenchymal transition

29 September 2017

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TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays

29 September 2017

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Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells

29 September 2017

1 reference

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Suppression of prostate cancer nodal and systemic metastasis by blockade of the lymphangiogenic axis

29 September 2017

1 reference

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Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma

29 September 2017

1 reference

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Direct regulation of TWIST by HIF-1alpha promotes metastasis

29 September 2017

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29 September 2017

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Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor

29 September 2017

1 reference

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Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

29 September 2017

1 reference

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Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

29 September 2017

1 reference

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Epithelial-mesenchymal transition and its implications for fibrosis

29 September 2017

1 reference

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Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

29 September 2017

1 reference

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

29 September 2017

1 reference

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A conserved family of prolyl-4-hydroxylases that modify HIF

29 September 2017

1 reference

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

29 September 2017

1 reference

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Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

29 September 2017

1 reference

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Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

Identification of the von Hippel-Lindau disease tumor suppressor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

Detailed genetic mapping of the von Hippel-Lindau disease tumour suppressor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

A murine renal cell carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

Conditional inactivation of the mouse von Hippel-Lindau tumor suppressor gene results in wide-spread hyperplastic, inflammatory and fibrotic lesions in the kidney.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

Deletions of chromosomes 3p and 14q molecularly subclassify clear cell renal cell carcinoma

4 September 2018

1 reference

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Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients

4 September 2018

1 reference

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Hypoxia-inducible factor 1 alpha in clear cell renal cell carcinoma

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

Regulation of E-cadherin expression by VHL and hypoxia-inducible factor.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4928183

The role of CXCR2/CXCR2 ligand biological axis in renal cell carcinoma

4 September 2018

1 reference

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Expression of MUC1 (EMA) and E-cadherin in renal cell carcinoma: a systematic immunohistochemical analysis of 188 cases

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27358011

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP29032

1 reference

18 August 2017

1 reference

18 August 2017

1 reference