Non-replication and inconsistency in the genome-wide association setting (Q36841272)

16 August 2017

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title

Non-replication and inconsistency in the genome-wide association setting (English)

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genome-wide association study

16 August 2017

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1

John P A Ioannidis

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language of work or name

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6 June 2007

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16 August 2017

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16 August 2017

64

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16 August 2017

4

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16 August 2017

203-213

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Mapping complex disease loci in whole-genome association studies

16 August 2017

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Recent developments in genomewide association scans: a workshop summary and review

21 January 2018

1 reference

Genome-wide association studies: theoretical and practical concerns

21 January 2018

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Genome-wide association studies for common diseases and complex traits

21 January 2018

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Genome-wide strategies for detecting multiple loci that influence complex diseases.

21 January 2018

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Optimal two-stage genotyping designs for genome-wide association scans

21 January 2018

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Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

21 January 2018

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Replication validity of genetic association studies

21 January 2018

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Genetic associations: false or true?

21 January 2018

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Complement factor H polymorphism in age-related macular degeneration

21 January 2018

1 reference

A common genetic variant is associated with adult and childhood obesity

21 January 2018

1 reference

High-resolution whole-genome association study of Parkinson disease.

21 January 2018

1 reference

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

21 January 2018

1 reference

Measuring inconsistency in meta-analyses

21 January 2018

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The balance between heritable and environmental aetiology of human disease

21 January 2018

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Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2

21 January 2018

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Breast cancer risks for BRCA1/2 carriers

21 January 2018

1 reference

Evaluating coverage of genome-wide association studies

21 January 2018

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Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies

21 January 2018

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Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases.

21 January 2018

1 reference

Genotyping errors: causes, consequences and solutions

21 January 2018

1 reference

Quantifying the percent increase in minimum sample size for SNP genotyping errors in genetic model-based association studies

21 January 2018

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Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies

21 January 2018

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Effect of population stratification on case-control association studies. II. False-positive rates and their limiting behavior as number of subpopulations increases.

21 January 2018

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Hidden population substructures in an apparently homogeneous population bias association studies.

21 January 2018

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The effects of human population structure on large genetic association studies

21 January 2018

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Effect of population stratification on case-control association studies. I. Elevation in false positive rates and comparison to confounding risk ratios (a simulation study).

21 January 2018

1 reference

Population structure, differential bias and genomic control in a large-scale, case-control association study

21 January 2018

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Genomic control, a new approach to genetic-based association studies

21 January 2018

1 reference

Matching strategies for genetic association studies in structured populations

21 January 2018

1 reference

Principal components analysis corrects for stratification in genome-wide association studies

21 January 2018

1 reference

Genetic association studies

21 January 2018

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Genetic associations in large versus small studies: an empirical assessment

21 January 2018

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A haplotype map of the human genome

21 January 2018

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Whole-genome patterns of common DNA variation in three human populations

21 January 2018

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Gene-environment interactions in human diseases

21 January 2018

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Statistical false positive or true disease pathway?

21 January 2018

1 reference

Hardy–Weinberg equilibrium in genetic association studies: an empirical evaluation of reporting, deviations and power

21 January 2018

1 reference

Case-Only Design to Measure Gene-Gene Interaction

21 January 2018

1 reference

Why most published research findings are false

21 January 2018

1 reference

27 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1371/JOURNAL.PMED.0020124

Identifiers

DOI

10.1159/000103512

1 reference

16 August 2017

1 reference

PubMed ID

17551261