Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function (Q36796699)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18450958%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function (English)

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6 January 2020

1

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6 January 2020

Thomas L Saunders

3

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6 January 2020

Alejandra M Pacchioni

4

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6 January 2020

Kurt Varner

7

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6 January 2020

Stephen M. Lanier

9

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6 January 2020

author name string

Kevin Lord

2

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6 January 2020

Cory Black

5

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6 January 2020

Eric Lazartigues

6

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6 January 2020

Thomas W Gettys

8

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6 January 2020

language of work or name

English

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publication date

1 May 2008

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6 January 2020

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6 January 2020

volume

149

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6 January 2020

page(s)

3842-3849

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6 January 2020

issue

8

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A specific role of AGS3 in the surface expression of plasma membrane proteins

6 January 2020

cites work

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Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling.

29 September 2017

1 reference

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Beta-adrenoceptor blocker treatment and the cardiac beta-adrenoceptor-G-protein(s)-adenylyl cyclase system in chronic heart failure

29 September 2017

1 reference

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Lysosomal phospholipase A2 and phospholipidosis

29 September 2017

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Adenosine A2a blockade prevents synergy between mu-opiate and cannabinoid CB1 receptors and eliminates heroin-seeking behavior in addicted rats

29 September 2017

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Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome

29 September 2017

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Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes

29 September 2017

1 reference

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Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior

29 September 2017

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Fat cells: afferent and efferent messages define new approaches to treat obesity

29 September 2017

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Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins

29 September 2017

1 reference

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Return of the GDI: the GoLoco motif in cell division.

29 September 2017

1 reference

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Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking.

29 September 2017

1 reference

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Beta-adrenergic receptors and regulation of energy expenditure: a family affair

29 September 2017

1 reference

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Inhibitory G-proteins and their role in desensitization of the adenylyl cyclase pathway in heart failure.

29 September 2017

1 reference

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Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Expression analysis and subcellular distribution of the two G-protein regulators AGS3 and LGN indicate distinct functionality. Localization of LGN to the midbody during cytokinesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Identification of a truncated form of the G-protein regulator AGS3 in heart that lacks the tetratricopeptide repeat domains.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Impaired vascular contractility and blood pressure homeostasis in the smooth muscle alpha-actin null mouse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Receptor-independent activators of heterotrimeric G-protein signaling pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

The GoLoco motif: a Galphai/o binding motif and potential guanine-nucleotide exchange factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Pertussis toxin-sensitive G-proteins and regulation of blood pressure in the spontaneously hypertensive rat

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A

29 September 2017

1 reference

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Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity

29 September 2017

1 reference

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Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

29 September 2017

1 reference

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Promotion of lipolysis in rat adipocytes by pertussis toxin: reversal of endogenous inhibition

29 September 2017

1 reference

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Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart

29 September 2017

1 reference

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Alterations in mRNA levels, expression, and function of GTP-binding regulatory proteins in adipocytes from obese mice (C57BL/6J-ob/ob).

29 September 2017

1 reference

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The effect of pertussis toxin on beta-adrenoceptor responses in isolated cardiac myocytes from noradrenaline-treated guinea-pigs and patients with cardiac failure

29 September 2017

1 reference

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The G-protein regulatory (GPR) motif-containing Leu-Gly-Asn-enriched protein (LGN) and Gialpha3 influence cortical positioning of the mitotic spindle poles at metaphase in symmetrically dividing mammalian cells.

29 September 2017

1 reference

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Modulation of basal and receptor-induced GIRK potassium channel activity and neuronal excitability by the mammalian PINS homolog LGN.

27 June 2018

1 reference

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G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Inactivation of enhanced expression of G(i) proteins by pertussis toxin attenuates the development of high blood pressure in spontaneously hypertensive rats

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

The Partner of Inscuteable/Discs-large complex is required to establish planar polarity during asymmetric cell division in Drosophila

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Enhanced expression of Gi-protein precedes the development of blood pressure in spontaneously hypertensive rats

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Increase of Gi alpha in human hearts with dilated but not ischemic cardiomyopathy

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Desensitization of adenylate cyclase and increase of Gi alpha in cardiac hypertrophy due to acquired hypertension

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryos.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Establishment and chimera analysis of 129/SvEv- and C57BL/6-derived mouse embryonic stem cell lines.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Rapsynoid/partner of inscuteable controls asymmetric division of larval neuroblasts in Drosophila.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2488243

A new approach to analysis of the arterial baroreflex

5 September 2018

1 reference

12 December 2020

Selective activation of inhibitory G-protein alpha-subunits by partial agonists of the human 5-HT1A receptor

1 reference

12 December 2020

Overexpression of Gi-proteins precedes the development of DOCA-salt-induced hypertension: relationship with adenylyl cyclase

1 reference

12 December 2020

Tumor necrosis factor alpha stimulates lipolysis in adipocytes by decreasing Gi protein concentrations

1 reference

12 December 2020

Growth hormone and dexamethasone stimulate lipolysis and activate adenylyl cyclase in rat adipocytes by selectively shifting Gi alpha2 to lower density membrane fractions

1 reference

12 December 2020

Desensitization of cardiac beta-adrenoceptor signaling with heart failure produced by myocardial infarction in the rat. Evidence for the role of Gi but not Gs or phosphorylating proteins

1 reference

12 December 2020

Increase in myocardial Gi-proteins in heart failure

1 reference

12 December 2020

Altered expression of inhibitory guanine nucleotide regulatory proteins (Gi alpha) in spontaneously hypertensive rats

1 reference

12 December 2020

DOCA-salt hypertensive rat hearts exhibit altered expression of G-proteins

1 reference

12 December 2020

Identifiers

DOI

10.1210/EN.2008-0050

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18450958%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18450958%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference