Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR. (Q36658914)

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8 March 2020

title

Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR (English)

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8 March 2020

4

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8 March 2020

Rens M J M de Vries

6

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8 March 2020

David Y. Thomas

9

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8 March 2020

Luc Brunsveld

10

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8 March 2020

8

Lech G Milroy

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8 March 2020

author name string

Loes M Stevers

1

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8 March 2020

Chan V Lam

2

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8 March 2020

Seppe F R Leysen

3

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8 March 2020

Daphne S van Scheppingen

5

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8 March 2020

Graeme W Carlile

7

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8 March 2020

Christian Ottmann

11

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8 March 2020

language of work or name

English

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publication date

17 February 2016

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Proceedings of the National Academy of Sciences of the United States of America

8 March 2020

published in

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volume

113

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8 March 2020

issue

9

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8 March 2020

page(s)

E1152-61

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The role of protein-protein interactions in the intracellular traffic of the potassium channels TASK-1 and TASK-3.

8 March 2020

cites work

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Protein intrinsic disorder and network connectivity. The case of 14-3-3 proteins

30 September 2017

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30 September 2017

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Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions

30 September 2017

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How good are my data and what is the resolution?

30 September 2017

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30 September 2017

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Rules for the recognition of dilysine retrieval motifs by coatomer

30 September 2017

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Stabilization and inhibition of protein-protein interactions: the 14-3-3 case study

30 September 2017

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Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock

30 September 2017

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Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis

30 September 2017

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Structural insights of the MLF1/14-3-3 interaction

30 September 2017

1 reference

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14-3-3 proteins as potential therapeutic targets

30 September 2017

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The scaffold protein Ste5 directly controls a switch-like mating decision in yeast

30 September 2017

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Structure of the p53 C-terminus bound to 14-3-3: implications for stabilization of the p53 tetramer

30 September 2017

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Bioinformatic and experimental survey of 14-3-3-binding sites.

30 September 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

30 September 2017

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30 September 2017

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MolProbity: all-atom structure validation for macromolecular crystallography

30 September 2017

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Recognition of an intra-chain tandem 14-3-3 binding site within PKCepsilon

30 September 2017

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30 September 2017

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Mechanism of direct bicarbonate transport by the CFTR anion channel

30 September 2017

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GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy

30 September 2017

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Low temperature induces the delivery of mature and immature CFTR to the plasma membrane

30 September 2017

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Correctors of protein trafficking defects identified by a novel high-throughput screening assay

30 September 2017

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Cystic fibrosis transmembrane regulator protein mutations: 'class' opportunity for novel drug innovation

30 September 2017

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Structure of a 14-3-3 coordinated hexamer of the plant plasma membrane H+ -ATPase by combining X-ray crystallography and electron cryomicroscopy

30 September 2017

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Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis

30 September 2017

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Structural basis for protein-protein interactions in the 14-3-3 protein family

30 September 2017

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14-3-3 proteins in membrane protein transport

30 September 2017

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14-3-3 proteins: a historic overview

30 September 2017

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Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

30 September 2017

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Scaling and assessment of data quality

30 September 2017

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Mechanism of chloride permeation in the cystic fibrosis transmembrane conductance regulator chloride channel

30 September 2017

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30 September 2017

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14-3-3 proteins--an update

30 September 2017

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Coot: model-building tools for molecular graphics

30 September 2017

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Structural view of a fungal toxin acting on a 14-3-3 regulatory complex

30 September 2017

1 reference

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Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals

30 September 2017

1 reference

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Cystic fibrosis: a worldwide analysis of CFTR mutations--correlation with incidence data and application to screening

30 September 2017

1 reference

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How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis

30 September 2017

1 reference

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Control of the cystic fibrosis transmembrane conductance regulator by alphaG(i) and RGS proteins

30 September 2017

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The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

30 September 2017

1 reference

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14-3-3 proteins: structure, function, and regulation

30 September 2017

1 reference

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Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding

30 September 2017

1 reference

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The structural basis for 14-3-3:phosphopeptide binding specificity

30 September 2017

1 reference

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

30 September 2017

1 reference

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Identification of the cystic fibrosis gene: chromosome walking and jumping

30 September 2017

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LRRK2 dephosphorylation increases its ubiquitination

30 September 2017

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The phytotoxin fusicoccin, a selective stabilizer of 14-3-3 interactions?

20 September 2018

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Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

20 September 2018

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Vesicular transport: the core machinery of COPI recruitment and budding

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26888287

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1516631113

1 reference

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8 March 2020

0 references

1 reference

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8 March 2020

1 reference