Interactome: gateway into systems biology (Q36257382)

13 August 2017

1 reference

title

Interactome: gateway into systems biology (English)

1 reference

13 August 2017

3

Marc Vidal

1 reference

13 August 2017

Michael E Cusick

1

1 reference

PubMed ID

16162640

13 August 2017

Niels Klitgord

series ordinal

2

1 reference

PubMed ID

16162640

13 August 2017

David E Hill

series ordinal

4

1 reference

13 August 2017

14 September 2005

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13 August 2017

Human Molecular Genetics

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13 August 2017

14 Spec No. 2

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13 August 2017

R171-81

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Lethality and centrality in protein networks

13 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Evidence for dynamically organized modularity in the yeast protein-protein interaction network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Integrating 'omic' information: a bridge between genomics and systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Protein interaction mapping in C. elegans using proteins involved in vulval development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A comprehensive two-hybrid analysis to explore the yeast protein interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A protein interaction map of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A map of the interactome network of the metazoan C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Functional organization of the yeast proteome by systematic analysis of protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Conservation of gene order: a fingerprint of proteins that physically interact

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Detecting protein function and protein-protein interactions from genome sequences

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Assigning protein functions by comparative genome analysis: Protein phylogenetic profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

MIPS: a database for genomes and protein sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Finishing the euchromatic sequence of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

The Pfam protein families database

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

The Gene Ontology (GO) database and informatics resource

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Moonlighting proteins: old proteins learning new tricks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

C. elegans ORFeome version 3.1: increasing the coverage of ORFeome resources with improved gene predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Closing in on the C. elegans ORFeome by cloning TWINSCAN predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Parallel identification of new genes in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Systematic discovery of new genes in the Saccharomyces cerevisiae genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

ORFeome cloning and systems biology: standardized mass production of the parts from the parts-list

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Empirical analysis of transcriptional activity in the Arabidopsis genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Complete sequencing and characterization of 21,243 full-length human cDNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Navigating the human transcriptome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Integrative annotation of 21,037 human genes validated by full-length cDNA clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Functional annotation of a full-length Arabidopsis cDNA collection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

The complete set of predicted genes from Saccharomyces cerevisiae in a readily usable form

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Open-reading-frame sequence tags (OSTs) support the existence of at least 17,300 genes in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

An ORFeome-based analysis of human transcription factor genes and the construction of a microarray to interrogate their expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A genome annotation-driven approach to cloning the human ORFeome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Human ORFeome version 1.1: a platform for reverse proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

1274 full-open reading frames of transcripts expressed in the developing mouse nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

The cell as a collection of protein machines: preparing the next generation of molecular biologists

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

From molecular to modular cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Modular organization of cellular networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Protein complexes and functional modules in molecular networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

hnRNP K: one protein multiple processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A network of protein-protein interactions in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Global protein function prediction from protein-protein interaction networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Network biology: understanding the cell's functional organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Reconstruction of cellular signalling networks and analysis of their properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Inferring network mechanisms: the Drosophila melanogaster protein interaction network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Subnets of scale-free networks are not scale-free: sampling properties of networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

On the structure of protein-protein interaction networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Protein interaction maps for model organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Yeast forward and reverse 'n'-hybrid systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Functional proteomics mapping of a human signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Affinity purification-mass spectrometry. Powerful tools for the characterization of protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Proteome analysis by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Local modeling of global interactome networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Computational genetics: finding protein function by nonhomology methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Analyzing cellular biochemistry in terms of molecular networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Who's your neighbor? New computational approaches for functional genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Experimental and bioinformatic approaches for interrogating protein-protein interactions to determine protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

BIND: the Biomolecular Interaction Network Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

The MIPS mammalian protein-protein interaction database

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Development of human protein reference database as an initial platform for approaching systems biology in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Identification of potential interaction networks using sequence-based searches for conserved protein-protein interactions or "interologs".

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Annotation transfer between genomes: protein-protein interologs and protein-DNA regulogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Online predicted human interaction database

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A Bayesian Networks Approach for Predicting Protein-Protein Interactions from Genomic Data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Predicting co-complexed protein pairs using genomic and proteomic data integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A first-draft human protein-interaction map

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A novel genetic system to detect protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

The protein-protein interaction map of Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Towards a proteome-scale map of the human protein–protein interaction network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Protein interaction maps on the fly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

High-throughput yeast two-hybrid assays for large-scale protein interaction mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Roles for the two-hybrid system in exploration of the yeast protein interactome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Systematic and large-scale two-hybrid screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

K+ channel interactions detected by a genetic system optimized for systematic studies of membrane protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Increasing specificity in high-throughput yeast two-hybrid experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A genetic strategy to eliminate self-activator baits prior to high-throughput yeast two-hybrid screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Filtering high-throughput protein-protein interaction data using a combination of genomic features

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

How biologically relevant are interaction-based modules in protein networks?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Gaining confidence in high-throughput protein interaction networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Accurate extraction of functional associations between proteins based on common interaction partners and common domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Protein interactions: two methods for assessment of the reliability of high throughput observations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A strategy for constructing large protein interaction maps using the yeast two-hybrid system: regulated expression arrays and two-phase mating

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Analyzing yeast protein-protein interaction data obtained from different sources

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Comparative assessment of large-scale data sets of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Protein interaction mapping: a Drosophila case study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A Drosophila protein-interaction map centered on cell-cycle regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

AVID: an integrative framework for discovering functional relationships among proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

An automated method for finding molecular complexes in large protein interaction networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Biochemical characterization of protein complexes from the Helicobacter pylori protein interaction map: strategies for complex formation and evidence for novel interactions within type IV secretion systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Shared components of protein complexes--versatile building blocks or biochemical artefacts?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Global organellar proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Integrated version of reverse two-hybrid system for the postproteomic era

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Single-gene disorders: what role could moonlighting enzymes play?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

An expanded view of bacterial DNA replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-beta signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Prediction of protein function using protein-protein interaction data

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

How reliable are experimental protein-protein interaction data?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Integrating functional genomics data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Kernel methods for predicting protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Relating whole-genome expression data with protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Back to the biology in systems biology: what can we learn from biomolecular networks?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Inferring protein-protein interactions through high-throughput interaction data from diverse organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Do current sequence analysis algorithms disclose multifunctional (moonlighting) proteins?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Protein interaction networks from yeast to human

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

On the number of protein-protein interactions in the yeast proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Towards an understanding of complex protein networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Combined functional genomic maps of the C. elegans DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A protein interaction framework for human mRNA degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

The yeast cell-cycle network is robustly designed

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Protein interaction networks in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

A biological atlas of functional maps

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Interrogating protein interaction networks through structural biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Bridging structural biology and genomics: assessing protein interaction data with known complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Protein interaction verification and functional annotation by integrated analysis of genome-scale data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Building with a scaffold: emerging strategies for high- to low-level cellular modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Robustness against mutations in genetic networks of yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Modularity and evolutionary constraint on proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Effect of sampling on topology predictions of protein-protein interaction networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

Guilt-by-association goes global

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI335

21 January 2018

Identifiers

DOI

10.1093/HMG/DDI335

1 reference

13 August 2017

1 reference

PubMed ID

16162640