Deficiency of Interleukin-15 Confers Resistance to Obesity by Diminishing Inflammation and Enhancing the Thermogenic Function of Adipose Tissues (Q36147727)

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English	Deficiency of Interleukin-15 Confers Resistance to Obesity by Diminishing Inflammation and Enhancing the Thermogenic Function of Adipose Tissues	scientific article

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scholarly article

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Europe PubMed Central

12 August 2017

Deficiency of Interleukin-15 Confers Resistance to Obesity by Diminishing Inflammation and Enhancing the Thermogenic Function of Adipose Tissues (English)

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Europe PubMed Central

12 August 2017

1 reference

GOA release 2020-03-11

negative regulation of cold-induced thermogenesis

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GOA release 2020-03-11

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GOA release 2020-03-11

Marek Rola-Pleszczynski

14

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Marek Rola-Pleszczynski

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author name string

Gregory Lacraz

1

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Europe PubMed Central

12 August 2017

Volatiana Rakotoarivelo

2

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Europe PubMed Central

12 August 2017

Sebastien M Labbé

3

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Europe PubMed Central

12 August 2017

Mathieu Vernier

4

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Europe PubMed Central

12 August 2017

Christophe Noll

5

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Europe PubMed Central

12 August 2017

Marian Mayhue

6

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12 August 2017

Jana Stankova

7

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12 August 2017

Adel Schwertani

8

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12 August 2017

Guillaume Grenier

9

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12 August 2017

André Carpentier

10

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12 August 2017

Denis Richard

11

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12 August 2017

Gerardo Ferbeyre

12

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12 August 2017

Julie Fradette

13

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12 August 2017

Alfredo Menendez

15

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12 August 2017

Marie-France Langlois

16

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12 August 2017

Subburaj Ilangumaran

17

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12 August 2017

Sheela Ramanathan

18

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12 August 2017

language of work or name

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publication date

29 September 2016

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12 August 2017

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Europe PubMed Central

12 August 2017

11

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12 August 2017

e0162995

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12 August 2017

9

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Europe PubMed Central

12 August 2017

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Creative Commons Attribution 4.0 International

29 September 2016

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April 2022 Public Data File from Crossref

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Interleukin-15-mediated inflammation promotes non-alcoholic fatty liver disease

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Trans-presentation of interleukin-15 by interleukin-15 receptor alpha is dispensable for the pathogenesis of autoimmune type 1 diabetes

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IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity.

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2 October 2017

18F-FDG PET/CT monitoring of β3 agonist-stimulated brown adipocyte recruitment in white adipose tissue

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Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity.

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Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer

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Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis

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Interleukin-15 and soluble interleukin-15 receptor α in coronary artery disease patients: association with epicardial fat and indices of adipose tissue distribution

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The biology of IL-15: implications for cancer therapy and the treatment of autoimmune disorders

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Bi-directional interconversion of brite and white adipocytes

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Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.

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Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis

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2 October 2017

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.

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2 October 2017

IL-15 overexpression promotes endurance, oxidative energy metabolism, and muscle PPARδ, SIRT1, PGC-1α, and PGC-1β expression in male mice

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The adipose organ: white-brown adipocyte plasticity and metabolic inflammation.

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2 October 2017

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human

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2 October 2017

Interleukin-15 treatment induces weight loss independent of lymphocytes.

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2 October 2017

Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans.

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2 October 2017

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

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2 October 2017

Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development

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2 October 2017

Loss of IL-15 receptor α alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles.

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2 October 2017

Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens

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2 October 2017

Low-grade hypothalamic inflammation leads to defective thermogenesis, insulin resistance, and impaired insulin secretion

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Oxidative stress in normal-weight obese syndrome.

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2 October 2017

Trans-presentation: a novel mechanism regulating IL-15 delivery and responses

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NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse

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2 October 2017

Functional brown adipose tissue in healthy adults

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Identification and importance of brown adipose tissue in adult humans

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Cold-activated brown adipose tissue in healthy men

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2 October 2017

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2 October 2017

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

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2 October 2017

Systemic elevation of interleukin-15 in vivo promotes apoptosis in skeletal muscles of young adult and aged rats

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2 October 2017

Preassociation of IL-15 with IL-15R alpha-IgG1-Fc enhances its activity on proliferation of NK and CD8+/CD44high T cells and its antitumor action

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Effects of IL-15 on rat brown adipose tissue: uncoupling proteins and PPARs

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The biological roles of exercise-induced cytokines: IL-6, IL-8, and IL-15.

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Transcriptional control of brown fat determination by PRDM16

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2 October 2017

Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist

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Brown adipose tissue: function and physiological significance

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

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Effects of interleukin-15 (IL-15) on adipose tissue mass in rodent obesity models: evidence for direct IL-15 action on adipose tissue

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Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity

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The uncoupling protein from brown fat mitochondria is related to the mitochondrial ADP/ATP carrier. Analysis of sequence homologies and of folding of the protein in the membrane.

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Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis.

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UCP1 mRNA does not produce heat.

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23 September 2018

Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse.

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23 September 2018

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23 September 2018

Brown adipose tissue activity controls triglyceride clearance.

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Exercise training versus diet-induced weight-loss on metabolic risk factors and inflammatory markers in obese subjects: a 12-week randomized intervention study

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23 September 2018

Production of a new tissue-engineered adipose substitute from human adipose-derived stromal cells.

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23 September 2018

Direct regulation of lipolysis by interleukin-15 in primary pig adipocytes.

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23 September 2018

Interleukin-15 treatment improves glucose homeostasis and insulin sensitivity in obese mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/27684068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-15 Contributes to the Regulation of Murine Adipose Tissue and Human Adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27684068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/27684068

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0162995

1 reference

Europe PubMed Central

12 August 2017

2016PLoSO..1162995L

0 references

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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