Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins (Q35859789)

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scientific article published in February 2012

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English	Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins	scientific article published in February 2012

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins (English)

1 reference

Europe PubMed Central

10 August 2017

1 reference

dihydroxymethoxychalcone

1 reference

1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one

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author name string

Vivek R Yadav

1

1 reference

Europe PubMed Central

10 August 2017

Sahdeo Prasad

2

1 reference

Europe PubMed Central

10 August 2017

Bharat B Aggarwal

3

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

1 February 2012

1 reference

Europe PubMed Central

10 August 2017

full work available at URL

https://europepmc.org/articles/pmc3315045?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1111/j.1476-5381.2011.01603.x?email=unpaywall_01@example.com

British Journal of Pharmacology

1 reference

Europe PubMed Central

10 August 2017

165

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Europe PubMed Central

10 August 2017

3

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Europe PubMed Central

10 August 2017

741-753

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Europe PubMed Central

10 August 2017

online access status

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1111/j.1476-5381.2011.01603.x?email=unpaywall_01@example.com

access restriction status

1 reference

based on heuristic

inferred from online access status

ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315045

11 July 2018

Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.

1 reference

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Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake

1 reference

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Butein sensitizes human hepatoma cells to TRAIL-induced apoptosis via extracellular signal-regulated kinase/Sp1-dependent DR5 upregulation and NF-kappaB inactivation

1 reference

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11 July 2018

Celastrol, a triterpene, enhances TRAIL-induced apoptosis through the down-regulation of cell survival proteins and up-regulation of death receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315045

11 July 2018

Cardamonin suppresses melanogenesis by inhibition of Wnt/beta-catenin signaling.

1 reference

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Peroxisome proliferator-activated receptor-gamma is essential in the pathogenesis of gastric carcinoma

1 reference

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Death receptor 5 promoter-enhancing compounds isolated from Catimbium speciosum and their enhancement effect on TRAIL-induced apoptosis.

1 reference

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Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells

1 reference

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Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.

1 reference

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Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2.

1 reference

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11 July 2018

The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages.

1 reference

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The clinical trail of TRAIL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315045

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Cardamonin inhibits COX and iNOS expression via inhibition of p65NF-kappaB nuclear translocation and Ikappa-B phosphorylation in RAW 264.7 macrophage cells

1 reference

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Blockade of nuclear factor-kappaB signaling pathway and anti-inflammatory activity of cardamomin, a chalcone analog from Alpinia conchigera

1 reference

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Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line

1 reference

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Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein

1 reference

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Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy.

1 reference

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c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315045

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CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315045

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Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers

1 reference

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Receptor-mediated choreography of life and death.

1 reference

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Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

1 reference

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Promoter structure and transcription initiation sites of the human death receptor 5/TRAIL-R2 gene

1 reference

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Tissue specific expression of p53 target genes suggests a key role for KILLER/DR5 in p53-dependent apoptosis in vivo.

1 reference

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Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

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Homozygous deletion of the death receptor DR4 gene in a nasopharyngeal cancer cell line is associated with TRAIL resistance

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Safety and antitumor activity of recombinant soluble Apo2 ligand

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KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

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Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

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An antagonist decoy receptor and a death domain-containing receptor for TRAIL

1 reference

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Inhibition of death receptor signals by cellular FLIP

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Specific interaction of chalcone-protein: cardamonin binding site II on the human serum albumin molecule

1 reference

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Dimethyl cardamonin inhibits lipopolysaccharide-induced inflammatory factors through blocking NF-kappaB p65 activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01603.X

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Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01603.X

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Antiproliferation of cardamonin is involved in mTOR on aortic smooth muscle cells in high fructose-induced insulin resistance rats

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The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01603.X

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Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel

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Comparison of the characterization on binding of alpinetin and cardamonin to lysozyme by spectroscopic methods

1 reference

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Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/21797841

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Expression of TRAIL (TNF-related apoptosis-inducing ligand) and its receptors in normal colonic mucosa, adenomas, and carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21797841

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inferred from PubMed ID database lookup

Cardamonin and alpinetin from the seeds of Amomum subulatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/21797841

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Cutting Edge: TRAIL Deficiency Accelerates Hematological Malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21797841

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Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through CHOP-independent DR5 upregulation

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https://pubmed.ncbi.nlm.nih.gov/21797841

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15-deoxy-Δ12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription

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https://pubmed.ncbi.nlm.nih.gov/21797841

12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2011.01603.X

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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