Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice (Q35034373)

5 August 2017

Noncanonical TGFβ signaling contributes to aortic aneurysm progression in Marfan syndrome mice (English)

1 reference

5 August 2017

1 reference

Bart L Loeys

11

0 references

author name string

Tammy M Holm

1

1 reference

5 August 2017

Jennifer P Habashi

2

1 reference

5 August 2017

Jefferson J Doyle

3

1 reference

5 August 2017

Djahida Bedja

4

1 reference

5 August 2017

YiChun Chen

5

1 reference

5 August 2017

Christel van Erp

6

1 reference

5 August 2017

Mark E Lindsay

7

1 reference

5 August 2017

David Kim

8

1 reference

5 August 2017

Florian Schoenhoff

9

1 reference

5 August 2017

Ronald D Cohn

10

1 reference

5 August 2017

Craig J Thomas

12

1 reference

5 August 2017

Samarjit Patnaik

13

1 reference

5 August 2017

Juan J Marugan

14

1 reference

5 August 2017

Daniel P Judge

15

1 reference

5 August 2017

Harry C Dietz

16

1 reference

5 August 2017

language of work or name

English

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publication date

1 April 2011

1 reference

5 August 2017

1 reference

5 August 2017

332

1 reference

5 August 2017

358-361

1 reference

5 August 2017

6027

1 reference

TGF-beta in the pathogenesis and prevention of disease: a matter of aneurysmic proportions

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

The extracellular matrix: not just pretty fibrils

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

RDEA119/BAY 869766: a potent, selective, allosteric inhibitor of MEK1/2 for the treatment of cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

New regulatory mechanisms of TGF-beta receptor function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Aneurysm syndromes caused by mutations in the TGF-beta receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Angiotensin II upregulates transforming growth factor-beta type I receptor on rat vascular smooth muscle cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Angiotensin II stimulates expression of transforming growth factor beta receptor type II in cultured mouse proximal tubular cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Giant aneurysms of the sinuses of Valsalva and aortic regurgitation in a patient with Noonan's syndrome.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3111087

Angiotensin II induces thrombospondin-1 production in human mesangial cells via p38 MAPK and JNK: a mechanism for activation of latent TGF-β1

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21493862

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Aneurysms of the sinuses of Valsalva in Noonan's syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21493862

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1192149

1 reference

5 August 2017

1 reference

5 August 2017

1 reference