Life is sweet! A novel role for N-glycans in Drosophila lifespan (Q34643533)

3 August 2017

Life is sweet! A novel role for N-glycans in Drosophila lifespan (English)

1 reference

3 August 2017

0 references

1 reference

Harry Schachter

1

1 reference

PubMed ID

21057214

3 August 2017

Gabrielle Boulianne

series ordinal

2

1 reference

3 August 2017

1 January 2011

1 reference

3 August 2017

1 reference

3 August 2017

5

1 reference

3 August 2017

18-24

1 reference

3 August 2017

1

1 reference

Neuronal expression of Mgat1 rescues the shortened life span of Drosophila Mgat11 null mutants and increases life span

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Metabolism, cell surface organization, and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

From the gamma-glutamyl cycle to the glycan cycle: a road with many turns and pleasant surprises

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Adaptive regulation at the cell surface by N-glycosylation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Long-lived Indy and calorie restriction interact to extend life span.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Analysis of cell surface proteome changes via label-free, quantitative mass spectrometry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Revealing the anti-HRP epitope in Drosophila and Caenorhabditis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Biosynthesis of truncated N-linked oligosaccharides results from non-orthologous hexosaminidase-mediated mechanisms in nematodes, plants, and insects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Complex N-glycan number and degree of branching cooperate to regulate cell proliferation and differentiation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

The Drosophila fused lobes gene encodes an N-acetylglucosaminidase involved in N-glycan processing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Structure of the mushroom bodies of the insect brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Modulation of neural carbohydrate epitope expression in Drosophila melanogaster cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Identification of the hydrophobic glycoproteins of Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Fucosyltransferase substrate specificity and the order of fucosylation in invertebrates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Protein glycosylation lessons from Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

A method for proteomic identification of membrane-bound proteins containing Asn-linked oligosaccharides

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Role of glycosylation in development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Synthesis of paucimannose N-glycans by Caenorhabditis elegans requires prior actions of UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I, alpha3,6-mannosidase II and a specific membrane-bound beta-N-acetylgluc

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

How does calorie restriction work?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Extended longevity in mice lacking the insulin receptor in adipose tissue

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Longevity determination genes in Drosophila melanogaster

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Golgi alpha-mannosidase II deficiency in vertebrate systems: implications for asparagine-linked oligosaccharide processing in mammals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Protein glycosylation: nature, distribution, enzymatic formation, and disease implications of glycopeptide bonds

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

The joys of HexNAc. The synthesis and function of N- and O-glycan branches

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Identification of core alpha 1,3-fucosylated glycans and cloning of the requisite fucosyltransferase cDNA from Drosophila melanogaster. Potential basis of the neural anti-horseadish peroxidase epitope.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Cloning and expression of Drosophila melanogaster UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Insect cells encode a class II alpha-mannosidase with unique properties

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

no-bridge and linotte act jointly at the interhemispheric junction to build up the adult central brain of Drosophila melanogaster.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Mechanisms of life span determination in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Extended life-span and stress resistance in the Drosophila mutant methuselah

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

The genetics of caloric restriction in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Characterisation of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A and its N-glycans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Post-translational modification of proteins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Drosophila insulin receptor: lectin-binding properties and a role for oxidation-reduction of receptor thiols in activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Insect cells contain an unusual, membrane-bound beta-N-acetylglucosaminidase probably involved in the processing of protein N-glycans.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

In vivo chemical modification of proteins (post-translational modification).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Central Dogma of Molecular Biology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Elevated paraquat resistance can be used as a bioassay for longevity in a genetically based long-lived strain ofDrosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

A structural basis for four distinct elution profiles on concanavalin A – Sepharose affinity chromatography of glycopeptides

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Characterization of an alpha-bungarotoxin binding component from Drosophila melanogaster

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Evidence for alternative splicing and developmental regulation of the Drosophila melanogaster Mgat2 (N-acetylglucosaminyltransferase II) gene.

7 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Null mutations in Drosophila N-acetylglucosaminyltransferase I produce defects in locomotion and a reduced life span.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Caenorhabditis elegans triple null mutant lacking UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

N-glycans are involved in the response of Caenorhabditis elegans to bacterial pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Extended life-span conferred by cotransporter gene mutations in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Realized immune response is enhanced in long-lived puc and chico mutants but is unaffected by dietary restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Defective neuronal development in the mushroom bodies of Drosophila fragile X mental retardation 1 mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

The Drosophila fragile X gene negatively regulates neuronal elaboration and synaptic differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

The Drosophila learning and memory gene linotte encodes a putative receptor tyrosine kinase homologous to the human RYK gene product.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Identification of linotte, a new gene affecting learning and memory in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Respective roles of the DRL receptor and its ligand WNT5 in Drosophila mushroom body development.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

The Drosophila castor gene is involved in postembryonic brain development.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Reconstitution in vitro of the GDP-fucose biosynthetic pathways of Caenorhabditis elegans and Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Drosophila regulatory factor X is necessary for ciliated sensory neuron differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FFLY.5.1.13920

Central brain postembryonic development in Drosophila: implication of genes expressed at the interhemispheric junction.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Development of Drosophila wing sensory neurons in mutants with missing or modified cell surface molecules.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052869

Alterations of life span in the nematode Caenorhabditis elegans under monoxenic culture conditions

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21057214

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Age-specific mortality and reproduction respond to adult dietary restriction in Drosophila melanogaster

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21057214

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/FLY.5.1.13920

1 reference

release_d6bo6tjz3fbnnb32k6q7r2upae

3 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/d6bo6tjz3fbnnb32k6q7r2upae

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3052869

1 reference

3 August 2017

1 reference

PubMed ID

21057214