In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes (Q34419646)

2 August 2017

In vivo effects of goldenseal, kava kava, black cohosh, and valerian on human cytochrome P450 1A2, 2D6, 2E1, and 3A4/5 phenotypes (English)

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6,7-Dimethoxy-3-(6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-2-benzofuran-1(3H)-one

2 August 2017

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Valeriana officinalis

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(2S,3R,4S,5R)-2-[(1S,1'S,4'R,5R,5'R,6'R,10'S,12'S,13'S,16'R,21'R)-4',5,6',12',17',17'-hexamethyl-3,6,9'-trioxaspiro[bicyclo[3.1.0]hexane-2,8'-hexacyclo[11.9.0.0¹,²¹.0⁴,¹².0⁵,¹⁰.0¹⁶,²¹]docosan]-4-oloxy]oxane-3,4,5-triol

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2

Stephanie F Gardner

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2 August 2017

Bill J Gurley

1

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2 August 2017

Martha A Hubbard

3

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2 August 2017

D Keith Williams

4

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2 August 2017

W Brooks Gentry

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2 August 2017

Ikhlas A Khan

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2 August 2017

Amit Shah

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2 August 2017

language of work or name

English

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publication date

1 May 2005

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full work available at URL

2 August 2017

https://europepmc.org/articles/pmc1894911?pdf=render

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19 March 2024

https://api.unpaywall.org/v2/10.1016/j.clpt.2005.01.009?email=unpaywall_01@example.com

published in

Clinical Pharmacology & Therapeutics

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2 August 2017

77

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2 August 2017

415-426

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2 August 2017

5

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https://api.unpaywall.org/v2/10.1016/j.clpt.2005.01.009?email=unpaywall_01@example.com

2 August 2017

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19 March 2024

access restriction status

open access

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inferred from online access status

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6 July 2018

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6 July 2018

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Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity

6 July 2018

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In vitro activity of commercial valerian root extracts against human cytochrome P450 3A4.

6 July 2018

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Multiple night-time doses of valerian (Valeriana officinalis) had minimal effects on CYP3A4 activity and no effect on CYP2D6 activity in healthy volunteers

27 October 2018

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27 October 2018

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Effects of kava (Kava-kava, 'Awa, Yaqona, Piper methysticum) on c-DNA-expressed cytochrome P450 enzymes and human cryopreserved hepatocytes

27 October 2018

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Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases

27 October 2018

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27 October 2018

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Influence of Goldenseal Root on the Pharmacokinetics of Indinavir

27 October 2018

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27 October 2018

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27 October 2018

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27 October 2018

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27 October 2018

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27 October 2018

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27 October 2018

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Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (Kava-Kava).

27 October 2018

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Inhibition of human cytochrome P450 activities by kava extract and kavalactones

27 October 2018

1 reference

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Cytochrome P450 phenotypic ratios for predicting herb-drug interactions in humans

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894911

Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894911

Valepotriates and valerenic acids in commercial preparations of valerian available in Australia.

27 October 2018

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Analysis of sesquiterpenes in Valeriana officinalis by capillary electrophoresis.

27 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1894911

Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin

27 October 2018

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Drug absorption in vitro model: filter-immobilized artificial membranes. 2. Studies of the permeability properties of lactones in Piper methysticum Forst

27 October 2018

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The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity

27 October 2018

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High-performance liquid chromatography determination of hydrastine and berberine in dietary supplements containing goldenseal

27 October 2018

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Indinavir concentrations and St John's wort.

27 October 2018

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Absorption, distribution and excretion of berberine

27 October 2018

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12 December 2020

Solid-phase extraction of midazolam and two of its metabolites from plasma for high-performance liquid chromatographic analysis

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12 December 2020

Improved high-performance liquid chromatographic determination of debrisoquine and 4-hydroxydebrisoquine in human urine following direct injection

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Determination of chlorzoxazone and 6-hydroxychlorzoxazone in human plasma and urine by high-performance liquid chromatography

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12 December 2020

An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures

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12 December 2020

Milk thistle, a herbal supplement, decreases the activity of CYP3A4 and uridine diphosphoglucuronosyl transferase in human hepatocyte cultures

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12 December 2020

Herbal supplements: a potential for drug interactions in transplant recipients

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12 December 2020

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12 December 2020

10.1016/J.CLPT.2005.01.009

Identifiers

DOI

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2 August 2017

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2 August 2017

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