Industrial choices for protein production by large-scale cell culture (Q34208136)

31 July 2017

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title

Industrial choices for protein production by large-scale cell culture (English)

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31 July 2017

Chu L

1

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PubMed ID

11287235

31 July 2017

Robinson DK

series ordinal

2

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31 July 2017

1 April 2001

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Current Opinion in Biotechnology

31 July 2017

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31 July 2017

12

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31 July 2017

2

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31 July 2017

180-187

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Large-scale production of mammalian cells and their products: engineering principles and barriers to scale-up

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Shear sensitivity of animal cells from a culture-medium perspective

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

A systematic approach to the validation of process control parameters for monoclonal antibody production in fed-batch culture of a murine myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Comparability testing of a humanized monoclonal antibody (Synagis) to support cell line stability, process validation, and scale-up for manufacturing

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activator

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

The gel microdrop secretion assay: Identification of a low productivity subpopulation arising during the production of human antibody in CHO cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

A comparison of different methods to determine the end of exponential growth in CHO cell cultures for optimization of scale-up.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

293SF metabolic flux analysis during cell growth and infection with an adenoviral vector

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Monitoring adenovirus infections with on-line and off-line methods

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Development of serum-free bioreactor production of recombinant human thyroid stimulating hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Influence of alterations in culture condition and changes in perfusion parameters on the retention performance of a 20 mum spinfilter during a perfusion cultivation of a recombinant CHO cell line in pilot scale

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Achievement of high cell density and high antibody productivity by a controlled-fed perfusion bioreactor process

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Complexity among constituents of the HLA-B*1501 peptide motif.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Large-scale production of natural cytokines during activation and expansion of human T lymphocytes in hollow fiber bioreactor cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Comparison of cell growth in T-flasks, in micro hollow fiber bioreactors, and in an industrial scale hollow fiber bioreactor system

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Computational and experimental investigation of flow and fluid mixing in the roller bottle bioreactor

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Long-term stable production of monocyte-colony inhibition factor (M-CIF) from CHO microcarrier perfusion cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Large-scale propagation of recombinant adherent cells that secrete a stable form of human glandular kallikrein, hK2.

1 reference

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7 January 2021

Pilot production of u-PA with porous microcarrier cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Expression, purification, and bioassay of human stanniocalcin from baculovirus-infected insect cells and recombinant CHO cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Continuous production and recovery of recombinant Ca2+ binding receptor from HEK 293 cells using perfusion through a packed bed bioreactor

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Production of HIV-1 gp120 in packed-bed bioreactor using the vaccinia virus/T7 expression system

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Measurement and control of dissolved carbon dioxide in mammalian cell culture processes using an in situ fiber optic chemical sensor

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Media formulation options and manufacturing process controls to safeguard against introduction of animal origin contaminants in animal cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

First steps in robot automation of sampling and sample management during cultivation of mammalian cells in pilot scale.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

Disposable bioreactor for cell culture using wave-induced agitation

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2800%2900197-X

7 January 2021

10.1016/S0958-1669(00)00197-X

Identifiers

DOI

1 reference

31 July 2017

1 reference

PubMed ID

11287235