Physical and functional interaction between p53 and the Werner's syndrome protein (Q33875710)

29 July 2017

Physical and functional interaction between p53 and the Werner's syndrome protein (English)

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29 July 2017

2

J Kipnis

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29 July 2017

G Blander

1

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29 July 2017

J F Leal

3

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29 July 2017

C E Yu

4

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29 July 2017

G D Schellenberg

5

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29 July 2017

M Oren

6

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29 July 2017

language of work or name

English

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publication date

1 October 1999

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Journal of Biological Chemistry

29 July 2017

7

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based on heuristic

inferred from page(s)

published in

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29 July 2017

274

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29 July 2017

41

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29 July 2017

29463-29469

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Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer

29 July 2017

1 reference

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p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

p53; from inductive signal to cellular effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Replicative senescence: implications for in vivo aging and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Increased activity of p53 in senescing fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

21 January 2018

1 reference

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Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1.

21 January 2018

1 reference

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p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs

21 January 2018

1 reference

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A Review of its Symptomatology, Natural History, Pathologic Features, Genetics And Relationship to the Natural Aging Process

21 January 2018

1 reference

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Progeroid syndromes: probing the molecular basis of aging?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

The gene responsible for Werner syndrome may be a cell division "counting" gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Positional cloning of the Werner's syndrome gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

The Werner syndrome protein is a DNA helicase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Homologous recombination is elevated in some Werner-like syndromes but not during normal in vitro or in vivo senescence of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

p53 modulation of TFIIH-associated nucleotide excision repair activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Phenotypic characterization of KU812, a cell line identified as an immature human basophilic leukocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Wild-type p53 can inhibit oncogene-mediated focus formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Suppression of human colorectal carcinoma cell growth by wild-type p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Allosteric activation of latent p53 tetramers

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Regulation of the specific DNA binding function of p53

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Replication focus-forming activity 1 and the Werner syndrome gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

The Bloom's syndrome gene product is homologous to RecQ helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

p53-mediated apoptosis is attenuated in Werner syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.41.29463

21 January 2018

Identifiers

DOI

10.1074/JBC.274.41.29463

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29 July 2017

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