Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation (Q33784627)

29 July 2017

Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation (English)

1 reference

genome-wide association study

29 July 2017

0 references

0 references

4

1 reference

29 July 2017

26

Igor Rudan

0 references

Veronique Vitart

9

Veronique Vitart

0 references

Lina Zgaga

19

Lina Zgaga

0 references

Ozren Polašek

7

Ozren Polašek

1 reference

29 July 2017

James F Wilson

21

0 references

Gordan Lauc

Gordan Lauc

1

0 references

Olga Gornik

Olga Gornik

8

0 references

Wei Wang

Wei Wang

17

0 references

Jodie L Abrahams

Jodie L Abrahams

10

0 references

Ulf Gyllensten

20

Ulf Gyllensten

1 reference

29 July 2017

24

Harry Campbell

1 reference

29 July 2017

15

Sarah H Wild

1 reference

29 July 2017

3

Jennifer E Huffman

1 reference

29 July 2017

23

Nicholas D Hastie

1 reference

29 July 2017

12

Mislav Novokmet

1 reference

29 July 2017

18

Ivana Kolčić

1 reference

29 July 2017

2

Abdelkader Essafi

1 reference

29 July 2017

6

Jayesh J Kattla

1 reference

29 July 2017

11

Maja Pučić

1 reference

29 July 2017

13

Irma Redžić

1 reference

29 July 2017

Ana Knežević

5

1 reference

29 July 2017

Susan Campbell

14

1 reference

29 July 2017

Fran Borovečki

16

1 reference

29 July 2017

Alan F Wright

22

1 reference

29 July 2017

Pauline M Rudd

25

1 reference

29 July 2017

23 December 2010

1 reference

29 July 2017

1 reference

29 July 2017

6

1 reference

29 July 2017

12

1 reference

29 July 2017

e1001256

1 reference

Creative Commons Attribution 4.0 International

29 July 2017

start time

23 December 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Epistasis of transcriptomes reveals synergism between transcriptional activators Hnf1alpha and Hnf4alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Complex genetic regulation of protein glycosylation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiov

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Mapping of HNF4alpha target genes in intestinal epithelial cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Adaptive regulation at the cell surface by N-glycosylation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

The effect of individual N-glycans on enzyme activity.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

New susceptibility locus for coronary artery disease on chromosome 3q22.3.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Glycosylation of serum proteins in inflammatory diseases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Common variants at 30 loci contribute to polygenic dyslipidemia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Human total serum N-glycome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Mammalian glycosylation in immunity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Genome wide prediction of HNF4alpha functional binding sites by the use of local and global sequence context

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Transcriptional regulation of the fucosyltransferase VI gene in hepatocellular carcinoma cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Biological function of fucosylation in cancer biology

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Glycan antagonists and inhibitors: a fount for drug discovery

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Family-based association tests for genomewide association scans

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Tissue-specific transcriptional regulation has diverged significantly between human and mouse

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Cycling of O-linked beta-N-acetylglucosamine on nucleocytoplasmic proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

GenABEL: an R library for genome-wide association analysis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Siglecs and their roles in the immune system

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

ECRbase: database of evolutionary conserved regions, promoters, and transcription factor binding sites in vertebrate genomes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Fucosylation in prokaryotes and eukaryotes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Glycosylation in cellular mechanisms of health and disease

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Genetic defects in the human glycome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Haploview: analysis and visualization of LD and haplotype maps

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Control of pancreas and liver gene expression by HNF transcription factors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Komrower Lecture. Congenital disorders of glycosylation (CDG): it's all in it!

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

The fucosyltransferase gene family: an amazing summary of the underlying mechanisms of gene evolution

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Fucose: biosynthesis and biological function in mammals

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Human disorders in N-glycosylation and animal models

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Score tests for association between traits and haplotypes when linkage phase is ambiguous

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Human alpha (1,3)-fucosyltransferase IV (FUTIV) gene expression is regulated by elk-1 in the U937 cell line

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Synthesis of GDP-L-fucose by the human FX protein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

A missense mutation in the FUT6 gene results in total absence of alpha3-fucosylation of human alpha1-acid glycoprotein

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

Structure-function studies on selectin carbohydrate ligands. Modifications to fucose, sialic acid and sulphate as a sialic acid replacement

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009678

HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software.

4 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

High-Throughput Glycome Analysis Is Set To Join High-Throughput Genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

Variability, heritability and environmental determinants of human plasma N-glycome

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

Common aberrations from the normal human plasma N-glycan profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

Hnf1alpha (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

Computational screening of conserved genomic DNA in search of functional noncoding elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

Discontinuation of fucose therapy in LADII causes rapid loss of selectin ligands and rise of leukocyte counts

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

GlycoBase and autoGU: tools for HPLC-based glycan analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

A new look at the statistical model identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001256

Stability of N-glycan profiles in human plasma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21203500

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Detailed structural analysis of N-glycans released from glycoproteins in SDS-PAGE gel bands using HPLC combined with exoglycosidase array digestions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21203500

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1001256

1 reference

29 July 2017

1 reference

29 July 2017

1 reference