A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53. (Q33292146)

25 July 2017

A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53. (English)

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E2F transcription factor 1

25 July 2017

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Poly(ADP-ribose) polymerase 1

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GRAM domain containing 4

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tumor protein p53

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Caspase 3

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Cytochrome c oxidase subunit 4I1

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positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

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author name string

Stanelle J

series ordinal

1

1 reference

PubMed ID

15565177

25 July 2017

Tu-Rapp H

series ordinal

2

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PubMed ID

15565177

25 July 2017

Pützer BM

series ordinal

3

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25 July 2017

1 April 2005

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Cell Death & Differentiation

25 July 2017

1 reference

25 July 2017

12

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25 July 2017

347-357

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25 July 2017

4

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401532

25 July 2017

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cites work

The regulation of E2F by pRB-family proteins

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7 January 2021

DP and E2F proteins: coordinating transcription with cell cycle progression.

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7 January 2021

Regulation of cell proliferation by the E2F transcription factors

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7 January 2021

Sibling rivalry in the E2F family

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7 January 2021

E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry

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7 January 2021

E2F-5, a new E2F family member that interacts with p130 in vivo

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7 January 2021

Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6

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7 January 2021

E2F-6, a member of the E2F family that can behave as a transcriptional repressor

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7 January 2021

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

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7 January 2021

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

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7 January 2021

Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation

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7 January 2021

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The retinoblastoma protein and cell cycle control

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7 January 2021

Distinct roles for E2F proteins in cell growth control and apoptosis

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7 January 2021

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

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7 January 2021

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

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7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

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7 January 2021

Specificity in the activation and control of transcription factor E2F-dependent apoptosis

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7 January 2021

E2F-1:DP-1 induces p53 and overrides survival factors to trigger apoptosis

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7 January 2021

p14ARF links the tumour suppressors RB and p53.

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7 January 2021

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

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7 January 2021

ARF differentially modulates apoptosis induced by E2F1 and Myc.

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7 January 2021

p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo

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7 January 2021

p19ARF targets certain E2F species for degradation.

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7 January 2021

E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis

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7 January 2021

E2F-1-induced p53-independent apoptosis in transgenic mice.

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7 January 2021

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

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7 January 2021

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

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7 January 2021

Apaf-1 is a transcriptional target for E2F and p53

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7 January 2021

Role for the p53 homologue p73 in E2F-1-induced apoptosis

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7 January 2021

Role of the p53-homologue p73 in E2F1-induced apoptosis

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7 January 2021

Identification of novel E2F1-regulated genes by microarray

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7 January 2021

Gene expression changes in response to E2F1 activation.

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7 January 2021

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

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7 January 2021

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

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7 January 2021

Improved safety through tamoxifen-regulated induction of cytotoxic genes delivered by Ad vectors for cancer gene therapy

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7 January 2021

Mechanism of E2F1-induced apoptosis in primary vascular smooth muscle cells.

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7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

Cell death: the significance of apoptosis

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7 January 2021

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

Caspases: enemies within

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

Direct coupling of the cell cycle and cell death machinery by E2F.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

Apaf-1 is a mediator of E2F-1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis

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7 January 2021

E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

The mitochondrial apoptosis-inducing factor plays a role in E2F-1-induced apoptosis in human colon cancer cells

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

A simplified system for generating recombinant adenoviruses

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: implications for tumorigenesis.

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401532

7 January 2021

Analysis of mitochondrial morphology and function with novel fixable fluorescent stains

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401532

1 reference

25 July 2017

1 reference

PubMed ID

15565177