Gelsolin (Q3098700)

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mammalian protein found in Homo sapiens
  • epididymis secretory sperm binding protein
  • brevin
  • GSN
  • gelsolin
  • actin-depolymerizing factor
  • ADF
  • AGEL
edit
Language Label Description Also known as
English
Gelsolin
mammalian protein found in Homo sapiens
  • epididymis secretory sperm binding protein
  • brevin
  • GSN
  • gelsolin
  • actin-depolymerizing factor
  • ADF
  • AGEL

Statements

molecular function
protein binding
determination method
IPI
9 references
retrieved
8 April 2019
stated in
Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396
determination method
IPI
retrieved
8 April 2019
stated in
Collagen remodeling by phagocytosis is determined by collagen substrate topology and calcium-dependent interactions of gelsolin with nonmuscle myosin IIA in cell adhesions
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396
determination method
IPI
retrieved
8 April 2019
stated in
Inhibition of prostate cancer cell growth by second-site androgen receptor antagonists
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396
determination method
IPI
retrieved
8 April 2019
stated in
Three-dimensional structure of cofilin bound to monomeric actin derived by structural mass spectrometry data
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396
determination method
IPI
retrieved
8 April 2019
stated in
The structural basis of actin interaction with multiple WH2/beta-thymosin motif-containing proteins.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396
determination method
IPI
retrieved
8 April 2019
stated in
Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396
determination method
IPI
retrieved
8 April 2019
stated in
Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396
determination method
IPI
retrieved
8 April 2019
stated in
Functional specialization of beta-arrestin interactions revealed by proteomic analysis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396
determination method
IPI
retrieved
8 April 2019
stated in
Ca2+ binding by domain 2 plays a critical role in the activation and stabilization of gelsolin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06396
determination method
IPI
cell component
extracellular region
determination method
NAS
IDA
ISS
TAS
IEA
6 references
retrieved
31 October 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
TAS
retrieved
31 October 2017
stated in
The human plasma proteome: a nonredundant list developed by combination of four separate sources
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
NAS
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
ISS
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IEA
retrieved
31 October 2017
stated in
Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IDA
retrieved
31 October 2017
stated in
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IDA
extracellular exosome
determination method
IDA
6 references
retrieved
31 October 2017
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IDA
retrieved
31 October 2017
stated in
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IDA
retrieved
31 October 2017
stated in
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IDA
retrieved
31 October 2017
stated in
Large-scale proteomics and phosphoproteomics of urinary exosomes
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IDA
retrieved
31 October 2017
stated in
Protein profile of exosomes from trabecular meshwork cells
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IDA
retrieved
31 October 2017
stated in
Proteomic analysis of podocyte exosome-enriched fraction from normal human urine
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IDA
extracellular region
determination method
HDA
IDA
IEA
ISS
NAS
TAS
6 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
TAS
retrieved
1 January 2018
stated in
The human plasma proteome: a nonredundant list developed by combination of four separate sources
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
NAS
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
ISS
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IEA
retrieved
1 January 2018
stated in
Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain
GOA
curator
UniProt
UniProt protein ID
P06396
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
IDA
retrieved
1 January 2018
stated in
Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P06396&geneProductId=UniProtKB:P06396
determination method
HDA
biological process
Gene Atlas image
PBB GE GSN 200696 s at fs.png
732 × 530; 12 KB
0 references

Identifiers

RefSeq protein ID
PDB structure ID
 
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