Brahma Dmel_CG5942 (Q29819687)

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Protein found in Drosophila melanogaster

brm
brm-PC
CG5942-PC
brm-PA
CG5942-PB
brm-PB
CG5942-PD
CG5942-PE
brm-PF
complementation group 3.5
brahma
brm-PD
brm-PE
CG5942-PA
CG5942 gene product from transcript CG5942-RD
CG5942-PF

Language	Label	Description	Also known as
English	Brahma Dmel_CG5942	Protein found in Drosophila melanogaster	brm brm-PC CG5942-PC brm-PA CG5942-PB brm-PB CG5942-PD CG5942-PE brm-PF complementation group 3.5 brahma brm-PD brm-PE CG5942-PA CG5942 gene product from transcript CG5942-RD CG5942-PF

Statements

1 reference

25 May 2022

UniProt protein ID

SWI/SNF complex subunit SMARCA2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

Bromodomain-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

BRK domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

SNF2-like, N-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

Glutamine-Leucine-Glutamine, QLQ, protein family

1 reference

based on heuristic

inferred from protein domain or family

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Helicase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

BRK domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Snf2, ATP coupling domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SNF2-related, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Helicase/SANT-associated domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

bromodomain protein family

1 reference

based on heuristic

inferred from protein domain or family

Bromodomain, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

helicase activity

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

protein binding

determination method

7 references

1 January 2018

Histone chaperone ASF1 cooperates with the Brahma chromatin-remodelling machinery

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

The Drosophila brahma complex is an essential coactivator for the trithorax group protein zeste

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

Reptin and Pontin function antagonistically with PcG and TrxG complexes to mediate Hox gene control

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

The Drosophila trithorax group proteins BRM, ASH1 and ASH2 are subunits of distinct protein complexes.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

The Drosophila brahma complex is an essential coactivator for the trithorax group protein zeste

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

Drosophila cyclin E interacts with components of the Brahma complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

ATP-dependent activity, acting on DNA

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

hydrolase activity

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

hydrolase activity, acting on acid anhydrides

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

histone binding

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

determination method

4 references

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

Differential targeting of two distinct SWI/SNF-related Drosophila chromatin-remodeling complexes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

The Drosophila BRM complex facilitates global transcription by RNA polymerase II

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

SWI/SNF complex

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

RSC-type complex

determination method

1 reference

1 January 2018

The transcriptional coactivator SAYP is a trithorax group signature subunit of the PBAP chromatin remodeling complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

biological process

chromatin remodeling

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

transcription, DNA-templated

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

1 January 2018

Akirin specifies NF-κB selectivity of Drosophila innate immune response via chromatin remodeling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

determination method

1 reference

1 January 2018

Identification of Drosophila gene products required for phagocytosis of Candida albicans

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

multicellular organism development

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

negative regulation of neuroblast proliferation

determination method

3 references

1 January 2018

The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

1 January 2018

Earmuff restricts progenitor cell potential by attenuating the competence to respond to self-renewal factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

determination method

1 reference

1 January 2018

Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

ventral cord development

determination method

1 reference

1 January 2018

Novel Genes Involved in Controlling Specification of Drosophila FMRFamide Neuropeptide Cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

imaginal disc-derived wing vein specification

determination method

1 reference

1 January 2018

The Drosophila Brahma (SWI/SNF) chromatin remodeling complex exhibits cell-type specific activation and repression functions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

imaginal disc-derived leg morphogenesis

determination method

1 reference

1 January 2018

The transcriptional coactivator SAYP is a trithorax group signature subunit of the PBAP chromatin remodeling complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

muscle organ development

determination method

1 reference

1 January 2018

Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

imaginal disc-derived wing vein morphogenesis

determination method

1 reference

1 January 2018

Osa, a subunit of the BAP chromatin-remodelling complex, participates in the regulation of gene expression in response to EGFR signalling in the Drosophila wing

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

imaginal disc-derived wing margin morphogenesis

determination method

1 reference

1 January 2018

Osa, a subunit of the BAP chromatin-remodelling complex, participates in the regulation of gene expression in response to EGFR signalling in the Drosophila wing

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

hemocyte proliferation

determination method

1 reference

1 January 2018

Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

intestinal stem cell homeostasis

determination method

1 reference

1 January 2018

Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

cell dedifferentiation

determination method

1 reference

1 January 2018

The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

histone H3-K27 acetylation

determination method

1 reference

1 January 2018

Histone demethylase UTX and chromatin remodeler BRM bind directly to CBP and modulate acetylation of histone H3 lysine 27.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

positive regulation of epidermal growth factor receptor signaling pathway

determination method

1 reference

1 January 2018

Geminin and Brahma act antagonistically to regulate EGFR-Ras-MAPK signaling in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

determination method

1 reference

1 January 2018

Chromatin remodeling enzymes: who's on first?

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

neuron development

determination method

1 reference

1 January 2018

Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

dendrite morphogenesis

determination method

dendrite guidance

determination method

1 reference

1 January 2018

The chromatin remodeling factor Bap55 functions through the TIP60 complex to regulate olfactory projection neuron dendrite targeting

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

regulation of neuroblast proliferation

determination method

1 reference

1 January 2018

Earmuff restricts progenitor cell potential by attenuating the competence to respond to self-renewal factors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

negative regulation of G1/S transition of mitotic cell cycle

determination method

1 reference

1 January 2018

Drosophila cyclin E interacts with components of the Brahma complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

positive regulation of stem cell proliferation

determination method

1 reference

1 January 2018

Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P25439&geneProductId=UniProtKB:P25439

determination method

Snf2, ATP coupling domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

Helicase, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

SNF2-related, N-terminal domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

Helicase/SANT-associated domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

Bromodomain, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

Glutamine-Leucine-Glutamine, QLQ

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

Helicase superfamily 1/2, ATP-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P25439

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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