Atypical protein kinase C Dmel_CG42783 (Q29809729)

Protein kinase-like domain superfamily

1 reference

Protein kinase C, PB1 domain, protein family

1 reference

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

Protein kinase, C-terminal domain, protein family

1 reference

PB1 domain, protein family

1 reference

Atypical protein kinase C, catalytic domain, protein family

1 reference

Diacylglycerol/phorbol-ester binding domain, protein family

1 reference

AGC-kinase, C-terminal domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

protein kinase activity

1 reference

8 April 2019

protein serine/threonine kinase activity

6 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9X0&geneProductId=UniProtKB:A1Z9X0

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9X0&geneProductId=UniProtKB:A1Z9X0

31 January 2018

aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division.

http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9X0&geneProductId=UniProtKB:A1Z9X0

31 January 2018

aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9X0&geneProductId=UniProtKB:A1Z9X0

31 January 2018

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9X0&geneProductId=UniProtKB:A1Z9X0

31 January 2018

Interplay between the transcription factor Zif and aPKC regulates neuroblast polarity and self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?protein=A1Z9X0&geneProductId=UniProtKB:A1Z9X0

protein kinase C activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

5 references

8 April 2019

A protein interaction map of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

protein serine/threonine kinase activity

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

Interplay between the transcription factor Zif and aPKC regulates neuroblast polarity and self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

Apicobasal polarization: epithelial form and function.

apical plasma membrane

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

The polarising role of cell adhesion molecules in early development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

The PAR complex regulates pulsed actomyosin contractions during amnioserosa apical constriction in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

5 references

8 April 2019

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

Twins/PP2A regulates aPKC to control neuroblast cell polarity and self-renewal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

The transcriptional response to tumorigenic polarity loss in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

establishment of mitotic spindle orientation

biological process

1 reference

8 April 2019

Drosophila aPKC is required for mitotic spindle orientation during symmetric division of epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

morphogenesis of a polarized epithelium

1 reference

8 April 2019

Apicobasal polarization: epithelial form and function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

positive regulation of neuroblast proliferation

TAS

1 reference

8 April 2019

Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

Protein kinases and phosphatases in the Drosophila genome

protein phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

cell-cell junction assembly

1 reference

8 April 2019

The polarising role of cell adhesion molecules in early development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

establishment or maintenance of cell polarity

NAS

3 references

8 April 2019

Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

Spermatid cyst polarization in Drosophila depends upon apkc and the CPEB family translational regulator orb2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

germarium-derived oocyte fate determination

1 reference

8 April 2019

Bazooka and atypical protein kinase C are required to regulate oocyte differentiation in the Drosophila ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

oocyte anterior/posterior axis specification

1 reference

8 April 2019

Lgl and its phosphorylation by aPKC regulate oocyte polarity formation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

New synaptic bouton formation is disrupted by misregulation of microtubule stability in aPKC mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

sensory organ development

1 reference

8 April 2019

Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

terminal branching, open tracheal system

1 reference

8 April 2019

Compensatory branching morphogenesis of stalk cells in the Drosophila trachea

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

positive regulation of lamellipodium assembly

1 reference

8 April 2019

Polarity proteins and Rho GTPases cooperate to spatially organise epithelial actin-based protrusions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

establishment or maintenance of polarity of follicular epithelium

1 reference

8 April 2019

Kinase-activity-independent functions of atypical protein kinase C in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

peptidyl-serine phosphorylation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

maintenance of cell polarity

IBA

1 reference

8 April 2019

Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

regulation of polarized epithelial cell differentiation

1 reference

8 April 2019

A Par-1-Par-3-Centrosome Cell Polarity Pathway and Its Tuning for Isotropic Cell Adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

adherens junction organization

1 reference

8 April 2019

aPKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

melanotic encapsulation of foreign target

1 reference

8 April 2019

A directed miniscreen for genes involved in the Drosophila anti-parasitoid immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

asymmetric protein localization involved in cell fate determination

1 reference

8 April 2019

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

apical protein localization

IPI

1 reference

8 April 2019

Protein localization during asymmetric cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

establishment or maintenance of neuroblast polarity

NAS

3 references

8 April 2019

Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

Kinase-activity-independent functions of atypical protein kinase C in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

8 April 2019

aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

establishment of epithelial cell apical/basal polarity

IGI

1 reference

8 April 2019

A bidirectional antagonism between aPKC and Yurt regulates epithelial cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

compound eye retinal cell programmed cell death

IGI

1 reference

8 April 2019

Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

positive regulation of filopodium assembly

1 reference

8 April 2019

Polarity proteins and Rho GTPases cooperate to spatially organise epithelial actin-based protrusions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

1 reference

8 April 2019

Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

asymmetric neuroblast division

1 reference

8 April 2019

Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

branching involved in open tracheal system development

IGI

1 reference

8 April 2019

A novel function for the PAR complex in subcellular morphogenesis of tracheal terminal cells in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

protein localization to plasma membrane

1 reference

8 April 2019

Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

regulation of intracellular mRNA localization

1 reference

8 April 2019

The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

Apicobasal polarization: epithelial form and function.

zonula adherens assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A1Z9X0

diacylglycerol/phorbol-ester binding

TAS

has part(s)

1 reference

protein kinase, C-terminal

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

PB1 domain

1 reference

AGC-kinase, C-terminal

1 reference

Atypical protein kinase C, catalytic domain

1 reference

serine/threonine-protein kinase, active site

1 reference

Protein kinase C, PB1 domain

1 reference