Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS (Q28589814)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

Catenin (cadherin associated protein), beta 1

30 January 2020

main subject

1 reference

GOA release 2020-03-11

1 reference

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

David Rowitch

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

Chao Zhao

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Dong-In Yuk

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Karen-Amanda Irvine

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Sovann Kaing

6

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Nader Sanai

7

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Stephen P J Fancy

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Sergio E Baranzini

2

1 reference

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30 January 2020

publication date

10 June 2009

1 reference

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30 January 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

volume

23

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

issue

13

2 references

31 January 2017

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30 January 2020

page(s)

1571-1585

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

17 March 2017

Dissecting demyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

LINGO-1 negatively regulates myelination by oligodendrocytes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Isolation and characterization of a novel human gene, DRCTNNB1A, the expression of which is down-regulated by beta-catenin

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Convergence of Wnt, beta-catenin, and cadherin pathways

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Remyelination in the CNS: from biology to therapy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma

9 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Multiple sclerosis: an immune or neurodegenerative disorder?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Novel TCF-binding sites specify transcriptional repression by Wnt signalling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Remyelination in experimental models of toxin-induced demyelination.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Remyelination can be extensive in multiple sclerosis despite a long disease course

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Mining the Wnt pathway for cancer therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from beta-catenin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Deficiency of hyccin, a newly identified membrane protein, causes hypomyelination and congenital cataract

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Remyelination is extensive in a subset of multiple sclerosis patients.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Multiple sclerosis--the plaque and its pathogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Regulation of oligodendrocyte development in the vertebrate CNS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Frizzled 8a function is required for oligodendrocyte development in the zebrafish spinal cord

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

T cells contribute to lysophosphatidylcholine-induced macrophage activation and demyelination in the CNS

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Transcription factor co-expression patterns indicate heterogeneity of oligodendroglial subpopulations in adult spinal cord.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Wnt signaling controls the timing of oligodendrocyte development in the spinal cord.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Re-expression of PSA-NCAM by demyelinated axons: an inhibitor of remyelination in multiple sclerosis?

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

Selective vulnerability of late oligodendrocyte progenitors to hypoxia-ischemia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2704469

A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19515974

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mouse brain organization revealed through direct genome-scale TF expression analysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19515974

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19515974

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.1806309

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19515974%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

2 references