The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism (Q28586580)

WW domain-containing oxidoreductase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Alain de Bruin

3

0 references

Stefano Volinia

object named as

Stefano Volinia

5

0 references

Carlo Maria Croce

12

object named as

Carlo M. Croce

1 reference

31 January 2017

10

Gary S. Stein

1 reference

31 January 2017

Rami I. Aqeilan

1

1 reference

31 January 2017

Mohammad Q. Hassan

2

1 reference

31 January 2017

John P. Hagan

4

1 reference

31 January 2017

Titziana Palumbo

6

1 reference

31 January 2017

Sadiq Hussain

7

1 reference

31 January 2017

Suk-Hee Lee

8

1 reference

31 January 2017

Tripti Gaur

9

1 reference

31 January 2017

Jane B. Lian

Journal of Biological Chemistry

11

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 August 2008

1 reference

31 January 2017

1 reference

31 January 2017

283

1 reference

31 January 2017

31

1 reference

31 January 2017

21629–21639

1 reference

31 January 2017

Targeted deletion of Wwox reveals a tumor suppressor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

TAZ, a transcriptional modulator of mesenchymal stem cell differentiation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

WW domain-containing proteins, WWOX and YAP, compete for interaction with ErbB-4 and modulate its transcriptional function

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Osteopetrosis-like phenotype in latent TGF-beta binding protein 3 deficient mice

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

The RUNX genes: gain or loss of function in cancer

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Functional association between Wwox tumor suppressor protein and p73, a p53 homolog

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

WWOX binds the specific proline-rich ligand PPXY: identification of candidate interacting proteins

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Bone defects in latent TGF-beta binding protein (Ltbp)-3 null mice; a role for Ltbp in TGF-beta presentation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

WWOX, the FRA16D gene, behaves as a suppressor of tumor growth

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

WWOX: a candidate tumor suppressor gene involved in multiple tumor types

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Regulation of chondrocyte differentiation by Cbfa1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

WWOX hypomorphic mice display a higher incidence of B-cell lymphomas and develop testicular atrophy.

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

WWOX in biological control and tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Physical association with WWOX suppresses c-Jun transcriptional activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

WWOX gene restoration prevents lung cancer growth in vitro and in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

The molecular actions of thyroid hormone in bone

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Isoform-specific regulation of platelet-derived growth factor activity and binding in osteoblast-enriched cultures from fetal rat bone

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo

29 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800855200

PKA-mediated protein phosphorylation regulates ezrin-WWOX interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800855200

Developmental expression and activities of specific fos and jun proteins are functionally related to osteoblast maturation: role of Fra-2 and Jun D during differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800855200

Perturbations in Bone Formation and Resorption in Insulin-Like Growth Factor Binding Protein-3 Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M800855200

Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2490770

The relationship between the GH/IGF-I axis and serum markers of bone turnover metabolism in healthy children

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18487609

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of platelet-derived growth factor-AA is associated with tumor progression in osteosarcoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18487609

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

WW domain-containing oxidoreductase: a candidate tumor suppressor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18487609