Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2 (Q28585632)

R-spondin 2

1 reference

Wingless-type MMTV integration site family, member 11

1 reference

Bone morphogenetic protein 2

1 reference

Transcription factor 7 like 2, T cell specific, HMG box

1 reference

Journal of Biological Chemistry

author name string

Michael S. Friedman

series ordinal

1

1 reference

31 January 2017

Sivan M. Oyserman

series ordinal

2

1 reference

31 January 2017

Kurt D. Hankenson

series ordinal

3

1 reference

31 January 2017

language of work or name

English

0 references

publication date

22 May 2009

1 reference

31 January 2017

1 reference

31 January 2017

284

1 reference

31 January 2017

21

1 reference

31 January 2017

14117–14125

1 reference

31 January 2017

R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Dentin matrix protein 1 regulates dentin sialophosphoprotein gene transcription during early odontoblast differentiation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Regulation of osteoblastogenesis and bone mass by Wnt10b

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

High bone density due to a mutation in LDL-receptor-related protein 5

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

A new mathematical model for relative quantification in real-time RT-PCR

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Isolation, characterisation and embryonic expression of WNT11, a gene which maps to 11q13.5 and has possible roles in the development of skeleton, kidney and lung

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Characterization of native and recombinant bone sialoprotein: delineation of the mineral-binding and cell adhesion domains and structural analysis of the RGD domain

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

R-Spondin family members regulate the Wnt pathway by a common mechanism

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

R-spondin1 synergizes with Wnt3A in inducing osteoblast differentiation and osteoprotegerin expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

R-Spondin proteins: a novel link to beta-catenin activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Regulation of mesenchymal stem cell and chondrocyte differentiation by MIA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Wnt signaling inhibits adipogenesis through beta-catenin-dependent and -independent mechanisms.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Beta-catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Standardized determination of real-time PCR efficiency from a single reaction set-up

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Wnt-3A enhances bone morphogenetic protein-2-mediated chondrogenesis of murine C3H10T1/2 mesenchymal cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Transcription factor Sp3 is essential for post-natal survival and late tooth development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682860

WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo.

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808337200

Wnt 3a promotes proliferation and suppresses osteogenic differentiation of adult human mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808337200

R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808337200

In vitro effects of dentin matrix protein-1 on hydroxyapatite formation provide insights into in vivo functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808337200

Bone regeneration is regulated by wnt signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M808337200

Synergistic activation of the murine gastrin promoter by oncogenic Ras and beta-catenin involves SMAD recruitment

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19213727

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

R-spondin2 expression in the apical ectodermal ridge is essential for outgrowth and patterning in mouse limb development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19213727

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M808337200

1 reference

1556058

1556058

1 reference

1 reference

1 reference