Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1 (Q28513162)

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16 January 2020

title

Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1 (English)

2 references

25 January 2017

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Mediator complex subunit 1

16 January 2020

main subject

1 reference

GOA release 2020-03-11

author

Hervé Luche

4

1 reference

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16 January 2020

author name string

Melanie Stumpf

1

2 references

25 January 2017

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16 January 2020

Xiaojing Yue

2

2 references

25 January 2017

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16 January 2020

Sandra Schmitz

3

2 references

25 January 2017

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16 January 2020

Tilman Borggrefe

6

2 references

25 January 2017

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16 January 2020

Janardan K Reddy

5

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language of work or name

English

0 references

publication date

23 November 2010

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

16 January 2020

published in

2 references

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volume

107

2 references

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issue

50

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page(s)

21541-21546

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GATA-1 associates with and inhibits p53.

16 January 2020

cites work

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The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220

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MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription

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Dynamic regulation of pol II transcription by the mammalian Mediator complex

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Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver

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Deletion of PBP/PPARBP, the gene for nuclear receptor coactivator peroxisome proliferator-activated receptor-binding protein, results in embryonic lethality

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The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion

19 March 2017

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Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor

19 March 2017

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FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation

19 March 2017

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Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

19 March 2017

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Inducible gene targeting in mice

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Differential coregulator requirements for function of the hematopoietic transcription factor GATA-1 at endogenous loci

7 April 2017

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BRG1 requirement for long-range interaction of a locus control region with a downstream promoter.

29 September 2017

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Transcriptional control of erythropoiesis: emerging mechanisms and principles.

29 September 2017

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Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation.

29 September 2017

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Long-range chromosomal interactions regulate the timing of the transition between poised and active gene expression

29 September 2017

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Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.

29 September 2017

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Role of the mediator complex in nuclear hormone receptor signaling.

29 September 2017

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On a chromosome far, far away: LCRs and gene expression

29 September 2017

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Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region

29 September 2017

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HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.

29 September 2017

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29 September 2017

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Mediator and the mechanism of transcriptional activation

29 September 2017

1 reference

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Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation

29 September 2017

1 reference

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29 September 2017

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29 September 2017

1 reference

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CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation

29 September 2017

1 reference

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Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells

29 September 2017

1 reference

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MED220/thyroid receptor-associated protein 220 functions as a transcriptional coactivator with Pit-1 and GATA-2 on the thyrotropin-beta promoter in thyrotropes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005794107

The HS2 enhancer of the beta-globin locus control region initiates synthesis of non-coding, polyadenylated RNAs independent of a cis-linked globin promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005794107

Structure and function of CRSP/Med2; a promoter-selective transcriptional coactivator complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005794107

Cdk1 Triggers Association of RNA Polymerase to Cell Cycle Promoters Only after Recruitment of the Mediator by SBF

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005794107

21 January 2018

Identifiers

DOI

10.1073/PNAS.1005794107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098667%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

1 reference

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16 January 2020

2 references

25 January 2017