IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses (Q28303437)

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20 January 2020

title

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses (English)

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20 January 2020

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1

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20 January 2020

Tracy Hussell

7

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20 January 2020

Irina Udalova

9

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20 January 2020

author name string

Katrina Blazek

2

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20 January 2020

Tim Smallie

3

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20 January 2020

Saba Alzabin

4

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20 January 2020

Helen Lockstone

5

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20 January 2020

Natasha Sahgal

6

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20 January 2020

Marc Feldmann

8

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20 January 2020

language of work or name

English

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publication date

16 January 2011

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20 January 2020

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20 January 2020

volume

12

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20 January 2020

issue

3

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20 January 2020

page(s)

231-238

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Exploring the full spectrum of macrophage activation

20 January 2020

cites work

1 reference

Alternative activation of macrophages

20 April 2017

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1 reference

A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

20 April 2017

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Cooperation between MyD88 and TRIF pathways in TLR synergy via IRF5 activation

20 April 2017

1 reference

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

20 April 2017

1 reference

Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms. Multiple isoforms with distinct cell type-specific expression, localization, regulation, and function

20 April 2017

1 reference

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus

20 April 2017

1 reference

Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

20 April 2017

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IRF5 is required for late-phase TNF secretion by human dendritic cells

20 April 2017

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Negative regulation of Toll-like-receptor signaling by IRF-4.

20 April 2017

1 reference

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

20 April 2017

1 reference

Interleukin-10: new perspectives on an old cytokine

20 April 2017

1 reference

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

20 April 2017

1 reference

Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease

20 April 2017

1 reference

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

20 April 2017

1 reference

Monocyte and macrophage heterogeneity

20 April 2017

1 reference

The regulation of IL-10 production by immune cells

20 April 2017

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

20 April 2017

1 reference

Th1/Th2 cells, their associated molecules and role in pathophysiology.

20 April 2017

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12 December 2020

Association of interferon regulatory factor 5 haplotypes, similar to that found in systemic lupus erythematosus, in a large subgroup of patients with rheumatoid arthritis

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12 December 2020

Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages.

1 reference

12 December 2020

Interleukin-23 drives intestinal inflammation through direct activity on T cells

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12 December 2020

IFN-alpha induces the human IL-10 gene by recruiting both IFN regulatory factor 1 and Stat3.

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12 December 2020

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

1 reference

12 December 2020

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on type I interferon signaling.

1 reference

12 December 2020

Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations

1 reference

12 December 2020

Association of an IRF5 gene functional polymorphism with Sjögren's syndrome

1 reference

12 December 2020

A proximal kappaB site in the IL-23 p19 promoter is responsible for RelA- and c-Rel-dependent transcription

1 reference

12 December 2020

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

1 reference

12 December 2020

The functional repertoires of metazoan genomes

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12 December 2020

IL-10 inhibits cytokine production by activated macrophages

1 reference

12 December 2020

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

1 reference

12 December 2020

An insertion-deletion polymorphism in the interferon regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases

1 reference

12 December 2020

Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice

1 reference

12 December 2020

Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation

1 reference

12 December 2020

Combined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signalling

1 reference

12 December 2020

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.

1 reference

12 December 2020

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

1 reference

12 December 2020

IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity

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12 December 2020

Colony-stimulating factors in inflammation and autoimmunity.

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12 December 2020

Granulocyte-macrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation

1 reference

12 December 2020

Properties and origin of human Th17 cells

1 reference

12 December 2020

Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock.

1 reference

12 December 2020

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

1 reference

12 December 2020

Interleukin-4 induced interferon regulatory factor (Irf) 4 participates in the regulation of alternative macrophage priming

1 reference

12 December 2020

Gender-dependent expression of murine Irf5 gene: implications for sex bias in autoimmunity

1 reference

12 December 2020

Transcriptional control of the inflammatory response

1 reference

12 December 2020

Macrophage activation and polarization

1 reference

12 December 2020

Macrophage biology and immunology: man is not a mouse.

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NI.1990

2 references

Consolidated OpenCitations Corpus – April 2017

550372

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21240265%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

550372

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

550372