RET/PTC rearrangement in thyroid tumors (Q28214459)

A novel type of RET rearrangement (PTC8) in childhood papillary thyroid carcinomas and characterization of the involved gene (RFG8)

Europe PubMed Central

title

RET/PTC rearrangement in thyroid tumors (English)

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author name string

Yuri E Nikiforov

series ordinal

1

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language of work or name

English

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publication date

2002

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published in

Endocrine Pathology

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volume

13

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issue

1

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page(s)

3-16

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cites work

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Struma lymphomatosa and carcinoma of the thyroid

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Detection of a novel type of RET rearrangement (PTC5) in thyroid carcinomas after Chernobyl and analysis of the involved RET-fused gene RFG5.

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Activation of a novel human transforming gene, ret, by DNA rearrangement

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ret rearrangements in Japanese pediatric and adult papillary thyroid cancers.

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Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.

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Development of a single-step duplex RT-PCR detecting different forms of ret activation, and identification of the third form of in vivo ret activation in human papillary thyroid carcinoma

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High prevalence of RET rearrangement in thyroid tumors of children from Belarus after the Chernobyl reactor accident

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Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children.

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ret/PTC-1 Activation in Hashimoto Thyroiditis

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Cytogenetic and molecular genetic characterization of papillary thyroid carcinomas

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Familial adenomatous polyposis-associated thyroid cancer: a clinical, pathological, and molecular genetics study

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Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

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GDNF family neurotrophic factor signaling: four masters, one servant?

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The transcription coactivator HTIF1 and a related protein are fused to the RET receptor tyrosine kinase in childhood papillary thyroid carcinomas

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12 December 2020

Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells

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12 December 2020

RET rearrangements in papillary thyroid carcinomas and adenomas detected by interphase FISH

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12 December 2020

Detection of RET oncogene activation in human papillary thyroid carcinomas by in situ hybridisation

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12 December 2020

Molecular analysis of new subtypes of ELE/RET rearrangements, their reciprocal transcripts and breakpoints in papillary thyroid carcinomas of children after Chernobyl

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12 December 2020

Detection of the PTC/retTPC oncogene in human thyroid cancers.

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12 December 2020

Papillary thyroid carcinoma oncogene (RET/PTC) alters the nuclear envelope and chromatin structure

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12 December 2020

Immunohistochemical Diagnosis of Papillary Thyroid Carcinoma

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12 December 2020

Cancer risks in patients with chronic lymphocytic thyroiditis

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12 December 2020

Preferential induction of RET/PTC1 rearrangement by X-ray irradiation

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12 December 2020

Detection of retTPC/PTC transcripts in thyroid adenomas and adenomatous goiter by an RT-PCR method

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12 December 2020

Involvement of RET oncogene in human tumours: specificity of RET activation to thyroid tumours

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12 December 2020

Leucine zipper-mediated dimerization is essential for the PTC1 oncogenic activity

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12 December 2020

Continued expression of a tissue specific activated oncogene in the early steps of radiation-induced human thyroid carcinogenesis

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12 December 2020

In vitro irradiation is able to cause RET oncogene rearrangement

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12 December 2020

RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes

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12 December 2020

The ret/PTC mutations are common in sporadic papillary thyroid carcinoma of children and young adults

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12 December 2020

Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes and Hirschsprung disease.

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12 December 2020

High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation

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12 December 2020

Distinct multiple RET/PTC gene rearrangements in multifocal papillary thyroid neoplasia

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12 December 2020

Different significance of ret/PTC(1) and ret/PTC(3) rearrangements in thyroid carcinogenesis: lesson from two subgroups of patients with papillary thyroid carcinomas showing the highest incidence of ret/PTC activation.

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12 December 2020

Prevalence of RET/PTC rearrangements in Hashimoto's thyroiditis and papillary thyroid carcinomas

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12 December 2020

RET/PTC rearrangements in thyroid nodules: studies in irradiated and not irradiated, malignant and benign thyroid lesions in children and adults

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12 December 2020

Prevalence and distribution of ret/ptc 1, 2, and 3 in papillary thyroid carcinoma in New Caledonia and Australia

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12 December 2020

Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications

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RET/NTRK1 rearrangements in thyroid gland tumors of the papillary carcinoma family: correlation with clinicopathological features.

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12 December 2020

Fusion of a novel gene, ELKS, to RET due to translocation t(10;12)(q11;p13) in a papillary thyroid carcinoma

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12 December 2020

Molecular basis off hurthle cell papillary thyroid carcinoma

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12 December 2020

Frequent activation of ret protooncogene by fusion with a new activating gene in papillary thyroid carcinomas.

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12 December 2020

RET/PTC and RET tyrosine kinase expression in adult papillary thyroid carcinomas

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12 December 2020

The RET/PTC3 oncogene: metastatic solid-type papillary carcinomas in murine thyroids

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12 December 2020

Cytogenetics and molecular genetics of carcinomas arising from thyroid epithelial follicular cells

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12 December 2020

Hyalinizing Trabecular Tumor of the Thyroid: A Variant of Papillary Carcinoma Proved By Molecular Genetics

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12 December 2020

Genetic alterations in thyroid carcinoma associated with familial adenomatous polyposis: clinical implications and suggestions for early detection

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12 December 2020

Low rate of ret proto-oncogene activation (PTC/retTPC) in papillary thyroid carcinomas from Saudi Arabia.

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12 December 2020

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12 December 2020

High prevalence of RET/PTC rearrangements in Ukrainian and Belarussian post-Chernobyl thyroid papillary carcinomas: a strong correlation between RET/PTC3 and the solid-follicular variant

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12 December 2020

RET/PCM-1: a novel fusion gene in papillary thyroid carcinoma

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12 December 2020

The RFG oligomerization domain mediates kinase activation and re-localization of the RET/PTC3 oncoprotein to the plasma membrane

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12 December 2020

ret/PTC-1, -2, and -3 oncogene rearrangements in human thyroid carcinomas: implications for metastatic potential?

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12 December 2020

Structure and expression of the ret transforming gene

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12 December 2020

Molecular characterization of RET/PTC3; a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma

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12 December 2020

Translocation t(10;14)(q11.2:q22.1) fusing the kinetin to the RET gene creates a novel rearranged form (PTC8) of the RET proto-oncogene in radiation-induced childhood papillary thyroid carcinoma

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12 December 2020

Low frequency of rearrangements of the ret and trk proto-oncogenes in Japanese thyroid papillary carcinomas

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12 December 2020

The TRK and RET tyrosine kinase oncogenes cooperate with ras in the neoplastic transformation of a rat thyroid epithelial cell line.

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12 December 2020

Development of thyroid papillary carcinomas secondary to tissue-specific expression of the RET/PTC1 oncogene in transgenic mice

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12 December 2020

The two genes generating RET/PTC3 are localized in chromosomal band 10q11.2.

1 reference

12 December 2020

Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI alpha of cyclic AMP-dependent protein kinase A

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12 December 2020

Ret oncogene activation in papillary thyroid carcinoma: prevalence and implication on the histological parameters.

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12 December 2020

Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas

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12 December 2020

RET/PTC activation in hyalinizing trabecular tumors of the thyroid

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12 December 2020

Oncogene profile of papillary thyroid carcinoma.

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12 December 2020

Detection of thyroglobulin, thyroid peroxidase, and RET/PTC1 mRNA transcripts in the peripheral blood of patients with thyroid disease

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12 December 2020

Sporadic ret-rearranged papillary carcinoma of the thyroid: a subset of slow growing, less aggressive thyroid neoplasms?

1 reference

12 December 2020

Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.

1 reference

12 December 2020

RET rearrangements in familial papillary thyroid carcinomas

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12 December 2020

Gene rearrangements in radiation-induced thyroid carcinogenesis

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12 December 2020

Solid variant of papillary thyroid carcinoma: incidence, clinical-pathologic characteristics, molecular analysis, and biologic behavior

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12 December 2020

Hyalinizing trabecular adenoma of the thyroid gland

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12 December 2020

Thyroid-stimulating hormone promotes growth of thyroid carcinomas in transgenic mice with targeted expression of the ret/PTC1 oncogene.

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12 December 2020

Frequent occurrence of cytogenetic abnormalities in sporadic nonmedullary thyroid carcinoma

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12 December 2020

RET/PTC oncogene activation is an early event in thyroid carcinogenesis.

1 reference

12 December 2020

Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident

1 reference

12 December 2020

PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas

1 reference

12 December 2020

Expression of the RET/PTC fusion gene as a marker for papillary carcinoma in Hashimoto's thyroiditis

1 reference

12 December 2020

Distinct frequency of ret rearrangements in papillary thyroid carcinomas of children and adults from Belarus

1 reference

12 December 2020

Tyrosines 1015 and 1062 are in vivo autophosphorylation sites in ret and ret-derived oncoproteins

1 reference

12 December 2020

The relationship between Hashimoto's thyroiditis, thyroid neoplasia, and primary hyperparathyroidism

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12 December 2020

The RET proto-oncogene in human cancers

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12 December 2020

Identifiers

DOI

10.1385/EP:13:1:03

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

3962877

1019931174

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Fatcat ID

release_oe7do4bygfgnxlmcroco6yjnjq

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Fatcat

https://api.fatcat.wiki/v0/release/oe7do4bygfgnxlmcroco6yjnjq

24 November 2022

mapped directly with Wikidata item

3962877

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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