Inhibitor of cyclooxygenase-2 induces cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin dependent kinase inhibitor p21 (Q28192797)

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scientific article (publication date: 8 April 2002)

Language	Label	Description	Also known as
English	Inhibitor of cyclooxygenase-2 induces cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin dependent kinase inhibitor p21	scientific article (publication date: 8 April 2002)

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scholarly article

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Inhibitor of cyclooxygenase-2 induces cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin dependent kinase inhibitor p21 (English)

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cancer cell line

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based on heuristic

inferred from title

author name string

T Toyoshima

1

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R Kamijo

2

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K Takizawa

3

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K Sumitani

4

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D Ito

5

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M Nagumo

6

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language of work or name

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publication date

8 April 2002

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British Journal of Cancer

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86

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7

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1150-6

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Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

20 March 2017

Cyclooxygenase in biology and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

20 March 2017

Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein

1 reference

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20 March 2017

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

20 March 2017

Human cyclooxygenase-2 cDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

20 March 2017

The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

1 reference

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20 March 2017

Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure

1 reference

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20 March 2017

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

20 March 2017

Inhibitors of mammalian G1 cyclin-dependent kinases

1 reference

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7 April 2017

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

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7 April 2017

Specific inhibition of cyclooxygenase-2 results in inhibition of proliferation of oral cancer cell lines via suppression of prostaglandin E2 production

1 reference

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29 September 2017

Enhanced expression of cyclooxygenase (COX)-2 in human skin epidermal cancer cells: evidence for growth suppression by inhibiting COX-2 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

Overexpression of cyclooxygenase-2 induces cell cycle arrest. Evidence for a prostaglandin-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

Expression of cyclooxygenase-2 in human lung carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

Aspirin use and potential mechanisms for colorectal cancer prevention

1 reference

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29 September 2017

Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

Cdk inhibitors in development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

Prostaglandin endoperoxide H synthases-1 and -2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

p53 in growth control and neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

Prostaglandin endoperoxide synthase: why two isoforms?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

Cyclooxygenase gene expression in inflammation and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

29 September 2017

Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

Novel intracellular signaling function of prostaglandin H synthase-1 in NF-kappa B activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

Regulation of p21WAF1/CIP1 expression by p53-independent pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

Differentiation of monocytoid THP-1 cells with phorbol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

Induction of WAF1/CIP1 by a p53-independent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

2 June 2018

Inhibitors of cyclooxygenase-2 (COX-2) suppressed the proliferation and differentiation of human leukaemia cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6600183

21 January 2018

Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJC.6600183

21 January 2018

Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2364196

27 November 2018

Induction of p27(KIP1) as a mechanism underlying NS398-induced growth inhibition in human lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ordering S phase and M phase in the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p21WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumorigenic transformation of immortalized ECV endothelial cells by cyclooxygenase-1 overexpression

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of macrophage cytokine production by prostaglandin E2. Distinct roles of cyclooxygenase-1 and -2

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 inhibitors in tumorigenesis (part I)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 inhibitors in tumorigenesis (Part II)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 expression in human esophageal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 expression is up-regulated in squamous cell carcinoma of the head and neck.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11953864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJC.6600183

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Springer Nature article ID

10.1038/sj.bjc.6600183

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