Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection (Q28119055)

SUMO transferase activity

GOA release 2020-03-11

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GOA release 2020-03-11

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Michael H. Tatham

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4 January 2017

Ronald T. Hay

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author name string

Suhkmann Kim

2

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4 January 2017

Ellis Jaffray

3

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4 January 2017

Jing Song

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4 January 2017

Yuan Chen

Nature Structural & Molecular Biology

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4 January 2017

1 January 2005

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4 January 2017

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4 January 2017

12

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4 January 2017

1

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4 January 2017

67–74

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4 January 2017

Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3

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Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

20 April 2017

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20 April 2017

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An E3-like factor that promotes SUMO conjugation to the yeast septins

20 April 2017

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A novel factor required for the SUMO1/Smt3 conjugation of yeast septins

20 April 2017

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PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription

20 April 2017

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Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

20 April 2017

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Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

20 April 2017

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The nucleoporin RanBP2 has SUMO1 E3 ligase activity

20 April 2017

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Structural insights into the U-box, a domain associated with multi-ubiquitination

20 April 2017

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Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation

20 April 2017

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A giant nucleopore protein that binds Ran/TC4

20 April 2017

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The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type

20 April 2017

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A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7

20 April 2017

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Stabilization of the E3 ubiquitin ligase Nrdp1 by the deubiquitinating enzyme USP8

20 April 2017

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PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

20 April 2017

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Ubch9 conjugates SUMO but not ubiquitin

20 April 2017

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Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system

20 April 2017

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Nuclear and unclear functions of SUMO

20 April 2017

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SUMO: ligases, isopeptidases and nuclear pores

20 April 2017

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PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.

21 January 2018

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The binding interface between an E2 (UBC9) and a ubiquitin homologue (UBL1).

21 January 2018

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The ubiquitin-conjugation system

21 January 2018

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Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation

21 January 2018

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Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358.

21 January 2018

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Identification of a SUMO-binding motif that recognizes SUMO-modified proteins

21 January 2018

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Protein interactions within the N-end rule ubiquitin ligation pathway

21 January 2018

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Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65.

21 January 2018

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Impact of transverse relaxation optimized spectroscopy (TROSY) on NMR as a technique in structural biology

21 January 2018

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