Brk is coamplified with ErbB2 to promote proliferation in breast cancer (Q28115616)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Brk is coamplified with ErbB2 to promote proliferation in breast cancer (English)

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

Protein tyrosine kinase 6

12 January 2020

main subject

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

author name string

Bin Xiang

1

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Haoqun Qiu

3

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Alexander Krasnitz

5

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Jim Hicks

6

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Min Yu

7

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

B Lakshmi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

W Todd Miller

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Senthil K Muthuswamy

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

language of work or name

English

0 references

publication date

21 August 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

12 January 2020

published in

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

volume

105

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

issue

34

2 references

3 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

page(s)

12463-12468

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition

12 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

20 March 2017

1 reference

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Cyclin E and survival in patients with breast cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation

20 March 2017

1 reference

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Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation

20 March 2017

1 reference

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Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers

20 March 2017

1 reference

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease

20 March 2017

1 reference

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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

20 March 2017

1 reference

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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

7 April 2017

1 reference

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Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

7 April 2017

1 reference

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EGF-ERBB signalling: towards the systems level

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

ERBB receptors and cancer: the complexity of targeted inhibitors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

PTK (protein tyrosine kinase)-6 and HER2 and 4, but not HER1 and 3 predict long-term survival in breast carcinomas.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Novel patterns of genome rearrangement and their association with survival in breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Cell cycle: sustained ERK signalling represses the inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

MAPK signal specificity: the right place at the right time

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Cyclin E as a prognostic and predictive marker in breast cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Interaction between Brk kinase and insulin receptor substrate-4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells

29 September 2017

1 reference

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The Brk protein tyrosine kinase as a therapeutic target in cancer: opportunities and challenges

29 September 2017

1 reference

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ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

29 September 2017

1 reference

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Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells

29 September 2017

1 reference

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The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer

29 September 2017

1 reference

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Epithelial mouse mammary cell line exhibiting normal morphogenesis in vivo and functional differentiation in vitro.

29 September 2017

1 reference

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Using three-dimensional acinar structures for molecular and cell biological assays.

29 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0805009105

Cyclin E is a more powerful predictor of breast cancer outcome than proliferation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0805009105

Advances in adjuvant therapy for breast cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2527934

New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18719096

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

BRK tyrosine kinase expression in a high proportion of human breast carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18719096

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0805009105

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

ADS bibcode

2008PNAS..10512463X

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18719096%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

2 references