The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses (Q27860685)

8

object named as

Shizuo Akira

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Makoto Miyagishi

object named as

Makoto Miyagishi

6

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Kazunari Taira

7

object named as

Kazunari Taira

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author name string

Mika Kikuchi

2

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Takashi Natsukawa

3

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Noriaki Shinobu

4

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Tadaatsu Imaizumi

5

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Takashi Fujita

Antiviral actions of interferons

9

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language of work or name

English

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publication date

July 2004

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published in

Nature Immunology

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volume

5

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issue

7

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page(s)

730-7

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cites work

1 reference

Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of the IFN-beta gene

21 April 2017

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Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

21 April 2017

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Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300.

21 April 2017

1 reference

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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1 reference

Triggering the interferon antiviral response through an IKK-related pathway

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

21 April 2017

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Recognition of single-stranded RNA viruses by Toll-like receptor 7

21 April 2017

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A Toll-like receptor recognizes bacterial DNA

21 April 2017

1 reference

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

21 April 2017

1 reference

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

21 April 2017

1 reference

IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein

21 April 2017

1 reference

The genetics of RNA silencing

21 April 2017

1 reference

mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties

21 April 2017

1 reference

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 April 2017

1 reference

CARD games in apoptosis and immunity

21 April 2017

1 reference

X-ray crystal structure of IRF-3 and its functional implications

21 April 2017

1 reference

Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

21 April 2017

1 reference

Toll-like receptors: critical proteins linking innate and acquired immunity

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1 reference

21 April 2017

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7 January 2021

Type I interferons and T helper development

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7 January 2021

Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

1 reference

7 January 2021

Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.

1 reference

7 January 2021

Involvement of a cis-element that binds an H2TF-1/NF kappa B like factor(s) in the virus-induced interferon-beta gene expression

1 reference

7 January 2021

The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction

1 reference

7 January 2021

An ATF/CREB binding site is required for virus induction of the human interferon beta gene [corrected].

1 reference

7 January 2021

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

1 reference

7 January 2021

Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex

1 reference

7 January 2021

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

1 reference

7 January 2021

CpG motifs in bacterial DNA and their immune effects

1 reference

7 January 2021

Bacterial induction of beta interferon in mice is a function of the lipopolysaccharide component

1 reference

7 January 2021

Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation

1 reference

7 January 2021

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

1 reference

7 January 2021

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

1 reference

7 January 2021

Viral infection switches non-plasmacytoid dendritic cells into high interferon producers.

1 reference

7 January 2021

PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus.

1 reference

7 January 2021

DExD/H box RNA helicases: from generic motors to specific dissociation functions

1 reference

7 January 2021

An RNA helicase, RHIV -1, induced by porcine reproductive and respiratory syndrome virus (PRRSV) is mapped on porcine chromosome 10q13.

1 reference

7 January 2021

NODs: intracellular proteins involved in inflammation and apoptosis

1 reference

7 January 2021

Activation of IFN-beta element by IRF-1 requires a posttranslational event in addition to IRF-1 synthesis

1 reference

7 January 2021

1 reference

7 January 2021

Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation

1 reference

7 January 2021

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways.

1 reference

7 January 2021

The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans

1 reference

7 January 2021

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

7 January 2021

Retinoic acid-inducible gene-I is induced in endothelial cells by LPS and regulates expression of COX-2.

1 reference

7 January 2021

Autocrine amplification of type I interferon gene expression mediated by interferon stimulated gene factor 3 (ISGF3).

1 reference

7 January 2021

Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation

1 reference

7 January 2021

Strategies for generation of an siRNA expression library directed against the human genome.

1 reference

7 January 2021

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

1 reference

7 January 2021