The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor (Q27732597)

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C Chène

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F K Winkler

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A Guha

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W H Konigsberg

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Y Nemerson

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D Kirchhofer

Activation of blood coagulation factor VIIa with cleaved tissue factor extracellular domain and crystallization of the active complex

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language of work or name

English

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publication date

7 March 1996

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published in

Nature

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volume

380

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page(s)

41-6

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issue

6569

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cites work

1 reference

7 January 2021

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque

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7 January 2021

Crystal structure of the extracellular region of human tissue factor

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Structure of the extracellular domain of human tissue factor: location of the factor VIIa binding site

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Mutational mapping of functional residues in tissue factor: identification of factor VII recognition determinants in both structural modules of the predicted cytokine receptor homology domain.

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Energetic contributions and topographical organization of ligand binding residues of tissue factor.

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Identification of the factor VIIa binding site on tissue factor by homologous loop swap and alanine scanning mutagenesis

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Analysis of the factor VIIa binding site on human tissue factor: effects of tissue factor mutations on the kinetics and thermodynamics of binding.

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Surface plasmon resonance studies of the interaction between factor VII and tissue factor. Demonstration of defective tissue factor binding in a variant FVII molecule (FVII-R79Q)

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Tissue factor: molecular recognition and cofactor function.

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The Ca2+ ion and membrane binding structure of the Gla domain of Ca-prothrombin fragment 1

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Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

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The first epidermal growth factor domain of human coagulation factor VII is essential for binding with tissue factor

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Involvement of the hydrophobic stack residues 39-44 of factor VIIa in tissue factor interactions

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7 January 2021

The importance of residues 195-206 of human blood clotting factor VII in the interaction of factor VII with tissue factor

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7 January 2021

Human factor VIIa and its complex with soluble tissue factor: evaluation of asymmetry and conformational dynamics by ultracentrifugation and fluorescence anisotropy decay methods

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Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor

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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

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Amino acid sequence and posttranslational modifications of human factor VIIa from plasma and transfected baby hamster kidney cells

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Structure of the calcium ion-bound gamma-carboxyglutamic acid-rich domain of factor IX

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Structure of the Ca(2+)-free Gla domain sheds light on membrane binding of blood coagulation proteins

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Two different Ca2+ ion binding sites in factor VIIa and in des(1-38) factor VIIa

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Structure of human des(1-45) factor Xa at 2.2 A resolution

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Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

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High affinity Ca(2+)-binding site in the serine protease domain of human factor VIIa and its role in tissue factor binding and development of catalytic activity

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A hot spot of binding energy in a hormone-receptor interface

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X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B

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7 January 2021

Proteolytic activation of human factors IX and X by recombinant human factor VIIa: effects of calcium, phospholipids, and tissue factor

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AMoRe: an automated package for molecular replacement

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7 January 2021

The CCP4 suite: programs for protein crystallography

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7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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