Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein (Q27731423)

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J P Noel

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H E Hamm

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P B Sigler

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language of work or name

English

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publication date

23 June 1994

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published in

Nature

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volume

369

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issue

6482

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page(s)

621-8

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The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

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A mutation that prevents GTP-dependent activation of the alpha chain of Gs.

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A site on rod G protein alpha subunit that mediates effector activation

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Identification of effector-activating residues of Gs alpha

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50 Transducin and the cyclic GMP phosphodiesterase of retinal rod outer segments

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