Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity (Q27661283)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20439752%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity (English)

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1 February 2020

1

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5

Titus J Boggon

1 reference

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1 February 2020

author name string

Andjelka Celic

2

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1 February 2020

Scott D Kennedy

3

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1 February 2020

Barbara E Ehrlich

4

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1 February 2020

Michael E Hodsdon

6

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1 February 2020

language of work or name

English

0 references

publication date

3 May 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20439752%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

1 February 2020

published in

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1 February 2020

volume

107

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1 February 2020

issue

20

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1 February 2020

page(s)

9176-9181

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Structural and molecular basis of the assembly of the TRPP2/PKD1 complex

1 February 2020

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20 March 2017

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Regulation of bestrophin Cl channels by calcium: role of the C terminus

20 March 2017

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20 March 2017

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The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation

20 March 2017

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Crystal structures of S100A6 in the Ca(2+)-free and Ca(2+)-bound states: the calcium sensor mechanism of S100 proteins revealed at atomic resolution

20 March 2017

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Polycystin-2 is an intracellular calcium release channel

20 March 2017

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PKD1 interacts with PKD2 through a probable coiled-coil domain

20 March 2017

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20 March 2017

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Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA

20 March 2017

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20 March 2017

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Errors in protein structures

20 March 2017

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20 March 2017

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Structures and metal-ion-binding properties of the Ca2+-binding helix-loop-helix EF-hand motifs

20 March 2017

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20 March 2017

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Regulation of calcium signaling by polycystin-2

20 March 2017

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Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

20 March 2017

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Evaluating protein structures determined by structural genomics consortia

20 March 2017

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Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2.

7 April 2017

1 reference

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New mutation of the Na channel in the severe form of potassium-aggravated myotonia.

29 September 2017

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Domain mapping of the polycystin-2 C-terminal tail using de novo molecular modeling and biophysical analysis

29 September 2017

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Calcium microdomains: organization and function

29 September 2017

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Contribution of potential EF hand motifs to the calcium-dependent gating of a mouse brain large conductance, calcium-sensitive K(+) channel

29 September 2017

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Identification and characterization of polycystin-2, the PKD2 gene product

29 September 2017

1 reference

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An interaction-based analysis of calcium-induced conformational changes in Ca2+ sensor proteins

29 September 2017

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Functional properties of intracellular calcium-release channels

29 September 2017

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NMR spectroscopy of hydroxyl protons in aqueous solutions of peptides and proteins.

29 September 2017

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29 September 2017

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Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.

2 June 2018

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2 June 2018

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Bell-shaped calcium-response curves of Ins(1,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum

2 June 2018

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Polycystin-2 associates with the polycystin-1 homolog, suREJ3, and localizes to the acrosomal region of sea urchin spermatozoa

2 June 2018

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Calcium dependence of polycystin-2 channel activity is modulated by phosphorylation at Ser812.

27 November 2018

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Ca2+ coordination to backbone carbonyl oxygen atoms in calmodulin and other EF-hand proteins: 15N chemical shifts as probes for monitoring individual-site Ca2+ coordination.

27 November 2018

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An effective method for the discrimination of motional anisotropy and chemical exchange

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20439752

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Tertiary Structure and Backbone Dynamics of Human Prolactin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20439752

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Somatic inactivation of Pkd2 results in polycystic kidney disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20439752

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0912295107

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20439752%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

ADS bibcode

2010PNAS..107.9176P

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20439752%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

2 references