Structure and dimerization of a soluble form of B7-1 (Q27621238)

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R J Gilbert

2

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J A Fennelly

3

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A V Collins

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K Harlos

5

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E Y Jones

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D I Stuart

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S J Davis

Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system

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language of work or name

English

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publication date

January 2000

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published in

Immunity

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volume

12

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issue

1

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page(s)

51-60

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cites work

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B70 antigen is a second ligand for CTLA-4 and CD28.

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Immunoglobulin fold characteristics of B7-1 (CD80) and B7-2 (CD86).

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Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution

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B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation

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A new member of the immunoglobulin superfamily--CTLA-4

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Effects of microheterogeneity on sedimentation patterns of interacting proteins and the sedimentation behavior of systems involving two ligands

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Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

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The structure and ligand interactions of CD2: implications for T-cell function

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The role of charged residues mediating low affinity protein-protein recognition at the cell surface by CD2

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CD2 and the nature of protein interactions mediating cell-cell recognition

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Establishing homologies in protein sequences

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Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area.

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A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

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Treatment of murine lupus with CTLA4Ig

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Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation

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Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice

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B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4.

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The immunological synapse: a molecular machine controlling T cell activation

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CD28/B7 costimulation: a review

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Transplantation of anergic histoincompatible bone marrow allografts

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CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

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Cloning, structural analysis, and mapping of the B30 and B7 multigenic families to the major histocompatibility complex (MHC) and other chromosomal regions

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Dali: a network tool for protein structure comparison

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ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

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Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2

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Improved methods for building protein models in electron density maps and the location of errors in these models

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

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Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

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Enhancement of antitumor immunity by CTLA-4 blockade

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Molecular basis of T cell inactivation by CTLA-4

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CD28/B7 system of T cell costimulation

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Cytotoxic T lymphocyte-associated molecule-4, a high-avidity receptor for CD80 and CD86, contains an intracellular localization motif in its cytoplasmic tail

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Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

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Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule

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Extending the B7 (CD80) gene family

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Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

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B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4)

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Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

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Expression, crystallization, and preliminary X-ray analysis of a sialic acid-binding fragment of sialoadhesin in the presence and absence of ligand

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The role of B7 co-stimulation in activation and differentiation of CD4+ and CD8+ T cells

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Raster3D Version 2.0. A program for photorealistic molecular graphics

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Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28

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Three-dimensional segregation of supramolecular activation clusters in T cells

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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CTLA-4 ligation suppresses CD28-induced NF-kappaB and AP-1 activity in mouse T cell blasts

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A chicken homologue of the co-stimulating molecule CD80 which binds to mammalian CTLA-4.

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Processing of X-ray diffraction data collected in oscillation mode

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Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28

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Protein volumes and hydration effects. The calculations of partial specific volumes, neutron scattering matchpoints and 280-nm absorption coefficients for proteins and glycoproteins from amino acid sequences.

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Crystal structure of the extracellular domain from P0, the major structural protein of peripheral nerve myelin

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CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28

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Cell adhesion. A birth certificate for CD2

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Boundary analysis in sedimentation transport experiments: a procedure for obtaining sedimentation coefficient distributions using the time derivative of the concentration profile

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Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A

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Bayesian correlated MAD phasing

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells

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Structure, interactions and dynamics of PRD1 virus I. Coupling of subunit folding and capsid assembly

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Topology of the CD2-CD48 cell-adhesion molecule complex: implications for antigen recognition by T cells

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7 January 2021

CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics

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7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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CTLA-4 can function as a negative regulator of T cell activation

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Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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The immunoglobulin superfamily--domains for cell surface recognition

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A receptor/cytoskeletal movement triggered by costimulation during T cell activation

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