RhoE binds to ROCK I and inhibits downstream signaling (Q24675619)

1

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Rosa M Guasch

2

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Ritu Garg

3

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Boquan Jin

Molecular and Cellular Biology

4

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language of work or name

English

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publication date

June 2003

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published in

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volume

23

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issue

12

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page(s)

4219-29

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cites work

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Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers.

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Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family

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Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

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A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion

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7 April 2017

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The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization

7 April 2017

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The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

7 April 2017

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Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase

7 April 2017

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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

7 April 2017

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Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation

7 April 2017

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Crystal structure of the core domain of RhoE/Rnd3: a constitutively activated small G protein

7 April 2017

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Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

7 April 2017

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Rho GTPases and the actin cytoskeleton

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

7 April 2017

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

7 April 2017

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RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain

7 April 2017

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Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

7 April 2017

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Rho-kinase--mediated contraction of isolated stress fibers

7 April 2017

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Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

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7 April 2017

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Rho GTPases and their effector proteins

7 April 2017

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Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

7 April 2017

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The Rho-associated protein kinase p160ROCK is required for centrosome positioning

7 April 2017

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Prolonged nuclear retention of activated extracellular signal-regulated kinase 1/2 is required for hepatocyte growth factor-induced cell motility

28 September 2017

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Regulation of protein transport from the Golgi complex to the endoplasmic reticulum by CDC42 and N-WASP.

28 September 2017

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Golgi vesicle proteins are linked to the assembly of an actin complex defined by mAbp1.

28 September 2017

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Characterization of RhoA-binding kinase ROKalpha implication of the pleckstrin homology domain in ROKalpha function using region-specific antibodies

28 September 2017

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Post-transcriptional down-regulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts

28 September 2017

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Antagonistic effects of Rnd1 and RhoD GTPases regulate receptor activity in Semaphorin 3A-induced cytoskeletal collapse.

28 September 2017

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Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

28 September 2017

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Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

28 September 2017

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Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells

28 September 2017

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Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway

28 September 2017

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The COOH terminus of Rho-kinase negatively regulates rho-kinase activity.

28 September 2017

1 reference

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Vesicle budding on Golgi membranes: regulation by G proteins and myosin motors

28 September 2017

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RhoE regulates actin cytoskeleton organization and cell migration.

28 September 2017

1 reference

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p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156133

Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156133

Different regions of Rho determine Rho-selective binding of different classes of Rho target molecules.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156133

Platelet-derived growth factor modulation of focal adhesion kinase (p125FAK) and paxillin tyrosine phosphorylation in Swiss 3T3 cells. Bell-shaped dose response and cross-talk with bombesin.

30 May 2018

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Ras signalling on the endoplasmic reticulum and the Golgi

30 May 2018

1 reference

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Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition

28 November 2018

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Erratum: Stress fibres take shape

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156133

Small GTPase RhoD suppresses cell migration and cytokinesis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=156133

Role of citron kinase as a target of the small GTPase Rho in cytokinesis.

28 November 2018

1 reference

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RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

28 November 2018

1 reference

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Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12773565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rho GTPases and their effector proteins

1 reference

Crossref

https://api.crossref.org/works/10.1128%2FMCB.23.12.4219-4229.2003

inferred from DOI database lookup

7 January 2021

based on heuristic

Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I gene

1 reference

Crossref

https://api.crossref.org/works/10.1128%2FMCB.23.12.4219-4229.2003

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1128/MCB.23.12.4219-4229.2003

1 reference

2367742

2367742

1 reference

1 reference

1 reference